ArticleAntioxidants (Basel, Switzerland)2019
Green Extraction Approaches for Carotenoids and Esters: Characterization of Native Composition from Orange Peel.
Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 70 citations in OpenAlex.
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- Article
- Agri-Food By-Products in Dairy Sector a Review Focused on Phytochemicals, Extraction Methods Health Benefits and Applications.Foods (Basel, Switzerland) · 2026Review
- Upcycled Orange Peel Ingredients: A Scoping Review on Phytochemical Composition, Extraction Techniques, and Biorefinery Strategies.Foods (Basel, Switzerland) · 2025Review
- Microwave-Assisted Extraction of Bioactive Compounds from Mandarin Peel: A Comprehensive Biorefinery Strategy.Antioxidants (Basel, Switzerland) · 2025Article
- Bioactive Compounds of Agro-Industrial By-Products: Current Trends, Recovery, and Possible Utilization.Antioxidants (Basel, Switzerland) · 2025Review
- Impact of Paracoccus sp. EGY7 carotenoids on triple-negative breast cancer cells: invitro study.AMB Express · 2025Article
- From byproduct to bioactive: genetic profiling, GC-MS, and nutritional analysis of citrus peel extracts for nutraceutical development.Frontiers in plant science · 2025Article
- Promising Phytogenic Feed Additives Used as Anti-Mycotoxin Solutions in Animal Nutrition.Toxins · 2024Review
- Comparative bioactivity assessment of bixin pigment and associated phytochemicals extracted from annatto seeds using conventional and green solvents.Journal of food and drug analysis · 2024Article
- Green Solvents for Extraction of Natural Food Colorants from Plants: Selectivity and Stability Issues.Foods (Basel, Switzerland) · 2024Review
- Unraveling the Potential of Orange Pulp for Improving Laying Rate, Egg Quality, Oxidative Stability, Fatty Acids Composition, and Reproductive Tract Morphology of Laying Hens.Animals : an open access journal from MDPI · 2023Article
- Article
- Green Solvents: Emerging Alternatives for Carotenoid Extraction from Fruit and Vegetable By-Products.Foods (Basel, Switzerland) · 2023Review
- Treatment with Supercritical COFoods (Basel, Switzerland) · 2023Article
- Food Wastes and Microalgae as Sources of Bioactive Compounds and Pigments in a Modern Biorefinery: A Review.Antioxidants (Basel, Switzerland) · 2023Review
- Carotenoids: Dietary Sources, Extraction, Encapsulation, Bioavailability, and Health Benefits-A Review of Recent Advancements.Antioxidants (Basel, Switzerland) · 2022Review
- Optimization of Ultrasound-Assisted Extraction and Encapsulation of Antioxidants from Orange Peels in Alginate-Chitosan Microparticles.Antioxidants (Basel, Switzerland) · 2022Article
- Bioactive Compounds of Citrus Fruits: A Review of Composition and Health Benefits of Carotenoids, Flavonoids, Limonoids, and Terpenes.Antioxidants (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Orange peel is a by-product produced in large amounts that acts as a source of natural pigments such as carotenoids. Xanthophylls, the main carotenoid class found in citrus fruit, can be present in its free form or esterified with fatty acids, forming esters. This esterification modifies the compound's chemical properties, affecting their bioavailability in the human body, and making it important to characterize the native carotenoid composition of food matrices. We aimed to evaluate the non-saponified carotenoid extracts of orange peel (cv. Pera) obtained using alternative green approaches: extraction with ionic liquid (IL), analyzed by high performance liquid chromatography coupled to a diode array detector with atmospheric pressure chemical ionization and mass spectrometry HPLC-DAD-APCI-MS, and supercritical fluid extraction (SFE), followed by supercritical fluid chromatography with atmospheric pressure chemical ionization and triple quadrupole mass spectrometry detection (SFC-APCI/QqQ/MS) in an online system. Both alternative green methods were successfully applied, allowing the total identification of five free carotenoids, one apocarotenoid, seven monoesters, and 11 diesters in the extract obtained with IL and analyzed by HPLC-DAD-APCI-MS, and nine free carotenoids, six carotenoids esters, 19 apocarotenoids, and eight apo-esters with the SFE-SFC-APCI/QqQ/MS approach, including several free apocarotenoids and apocarotenoid esters identified for the first time in oranges, and particularly in the Pera variety, which could be used as a fruit authenticity parameter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.