Evidence map›Paper›PMID 31816878›Full record

ArticleMolecules (Basel, Switzerland)2019

7-

Wesley F Taylor, Maria Yanez, Sara E Moghadam, Mahdi Moridi Farimani, Sara Soroury, Samad N Ebrahimi, Marzieh Tabefam, Ehsan Jabbarzadeh

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Natural medicine delivery from 3D printed bone substitutes.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  4. Review
  5. Article
  6. Life (Basel, Switzerland) · 2021
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wesley F TaylorDepartment of Chemical Engineering, University of South Carolina, Columbia, SC 29208, USA.
Maria YanezDepartment of Chemical Engineering, University of South Carolina, Columbia, SC 29208, USA.
Sara E MoghadamDepartment of Chemical Engineering, University of South Carolina, Columbia, SC 29208, USA.
Mahdi Moridi FarimaniDepartment of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G. C., Evin, Tehran 19839-69411, Iran.ORCID 0000-0001-9273-1019
Sara SorouryDepartment of Phytochemistry, Faculty of Science, Golestan University, Gorgan 15759-49138, Iran.
Samad N EbrahimiDepartment of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G. C., Evin, Tehran 19839-69411, Iran.ORCID 0000-0003-2167-8032
Marzieh TabefamDepartment of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G. C., Evin, Tehran 19839-69411, Iran.
Ehsan JabbarzadehDepartment of Chemical Engineering, University of South Carolina, Columbia, SC 29208, USA.

Funding

Targeting early ceramide elevation in pre-symptomatic eczemaP20GM103641 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ENOS, REILLY, NAGARKATTI, PRAKASH S · 2012 to 2023
$20.7M
NIH HHS P20 GM103641
6 · The paper itself

Abstract

Targeted therapies have changed the treatment of cancer, giving new hope to many patients in recent years. The shortcomings of targeted therapies including acquired resistance, limited susceptible patients, high cost, and high toxicities, have led to the necessity of combining these therapies with other targeted or chemotherapeutic treatments. Natural products are uniquely capable of synergizing with targeted and non-targeted anticancer regimens due to their ability to affect multiple cellular pathways simultaneously. Compounds which provide an additive effect to the often combined immune therapies and cytotoxic chemotherapies, are exceedingly rare. These compounds would however provide a strengthening bridge between the two treatment modalities, increasing their effectiveness and improving patient prognoses. In this study, 7-

Indexed as

Angiogenesis InhibitorsAntineoplastic AgentsBenzophenonesBenzoquinonesBiological ProductsCell Line, TumorCell MovementCell ProliferationCell SurvivalDrug Screening Assays, AntitumorHumansImmunologic FactorsMolecular Structure7-epiclusianoneAngiogenesis InhibitorsAntineoplastic AgentsBenzophenonesBenzoquinonesBiological ProductsImmunologic Factorscancerchemotherapeuticsimmunomodulationmultitargetingnatural compounds

Identifiers

PMID31816878
PMCPMC6930650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.