Evidence map›Paper›PMID 31816861›Full record

ArticleNutrients2019

Whey Protein Hydrolysate and Pumpkin Pectin as Nutraceutical and Prebiotic Components in a Functional Mousse with Antihypertensive and Bifidogenic Properties.

Evgeniya Yu Agarkova, Alexandr G Kruchinin, Olga A Glazunova, Tatyana V Fedorova

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Pumpkin Seeds as a Natural Remedy for Anemia: Nutritional Insights and Therapeutic Potential.Current therapeutic research, clinical and experimental · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Regulatory effect of gut microbes on blood pressure.Animal models and experimental medicine · 2022
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Evgeniya Yu AgarkovaAll-Russian Research Institute of Dairy Industry, Moscow 115093, Russia.
Alexandr G KruchininAll-Russian Research Institute of Dairy Industry, Moscow 115093, Russia.
Olga A GlazunovaA. N. Bach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russia.ORCID 0000-0002-9001-4072
Tatyana V FedorovaA. N. Bach Institute of Biochemistry, Research Centre of Biotechnology of the Russian Academy of Sciences, Moscow 119071, Russia.ORCID 0000-0002-0355-6800
All-Russian Scientific Research Institute of the Dairy Industry · RUA N Bach Institute of Biochemistry · RU

Funding

Russian Science Foundation 16-16-00094
6 · The paper itself

Abstract

Systematical consumption of functional products has a significant positive effect on health and can reduce the risk of diseases. The aim of this study was to investigate the possibility of using whey protein hydrolysate (WPH) and pumpkin pectin as ingredients in a functional mousse, to evaluate the mousse's antioxidant and hypotensive activities in vitro, and to evaluate the effect of the long-term intake of mousse samples on the progression of hypertension in spontaneously hypertensive rats (SHRs) and on the microbiome status in Wistar rats with antibiotic-induced dysbiosis. The experimental mousse's in vitro antioxidant activity (oxygen radical absorbance capacity) increased by 1.2 times. The hypotensive (angiotensin-1-converting enzyme inhibitory) activity increased by 6 times in comparison with a commercial mousse. Moreover, the addition of pectin allowed the elimination of the bitter aftertaste of WPH. In vivo testing confirmed the hypotensive properties of the experimental mousse. The systolic blood pressure in SHRs decreased by 18 mmHg and diastolic blood pressure by 12 mmHg. The experimental mousse also showed a pronounced bifidogenic effect. The

Indexed as

Dietary SupplementsPrebioticsAngiotensin-Converting Enzyme InhibitorsAnimalsAnti-Bacterial AgentsAntihypertensive AgentsAntioxidantsBifidobacteriumCucurbitaDysbiosisEnrofloxacinFunctional FoodGastrointestinal MicrobiomeMalePectinsRatsAngiotensin-Converting Enzyme InhibitorsAnti-Bacterial AgentsAntihypertensive AgentsAntioxidantsEnrofloxacinPectinsPrebioticsWhey Proteinsantioxidant activityfunctional foodhypotensive propertiesmoussepumpkin pectinwhey protein hydrolysates

Identifiers

PMID31816861
PMCPMC6950020
OpenAlexW2994293295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.