ArticleGigaScience2019
Pseudo-chromosome-length genome assembly of a double haploid "Bartlett" pear (Pyrus communis L.).
Article in GigaScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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Who cites it
66 citing papers in PubMed, 128 citations in OpenAlex.
- A high-quality haplotype-resolved genome of Pyrus calleryana provides insights into adaptive gene families.The plant genome · 2026Article
- Diversity parameter calculation from SSR data with varying and higher ploidy levels: an example on pear (Pyrus ssp.) data.BMC research notes · 2026Article
- Pangenome-wide identification of chloroplast RNA splicing and ribosome maturation (CRM) genes in eight Pyrus genomes indicated their involvement in multiple stresses.Scientific reports · 2026Article
- Haplotype-resolved chromosome-level genome assemblies of nineteen apple (Malus domestica Borkh.) cultivars.Scientific data · 2026Article
- Orchard and storage-dependent metabolic and transcriptional regulation of superficial scald in 'Packham's Triumph' pears.Frontiers in plant science · 2026Article
- The origin and evolution of HKT proteins with TrkH domain from aquatic plants to flowering plants.Horticulture research · 2025Article
- Development and application of a multiple nucleotide polymorphism (MNP)-based molecular identification system for pear cultivars.BMC plant biology · 2025Article
- Pear scab resistance gene Rvn1 from Ussurian pear is located in a cluster of receptor-like protein ethylene-inducing Xylanase (EIX) genes.BMC plant biology · 2025Article
- Naturally impaired side-chain shortening of aromatic 3-ketoacyl-CoAs reveals the biosynthetic pathway of plant acetophenones.Nature plants · 2025Article
- Comparative genomic analyses reveal different genetic basis of two types of fruit in Maloideae.Nature communications · 2025Article
- Haplotype-resolved, gap-free genome assemblies provide insights into the divergence between Asian and European pears.Nature genetics · 2025Article
- Haplotype-resolved T2T genome assembly of the pear cultivar 'Danxiahong'.Scientific data · 2025Article
- Article
- Gap-free genome assemblies of two Pyrus bretschneideri cultivars and GWAS analyses identify a CCCH zinc finger protein as a key regulator of stone cell formation in pear fruit.Plant communications · 2025Article
- Long-read genome sequencing reveals the sequence characteristics of pear self-incompatibility locus.Molecular horticulture · 2025Article
- Telomere-to-telomere Genome Assembly of two representative Asian and European pear cultivars.Scientific data · 2024Article
- Haplotype-resolved T2T genome assemblies and pangenome graph of pear reveal diverse patterns of allele-specific expression and the genomic basis of fruit quality traits.Plant communications · 2024Article
- Advancing apple genetics research: Malus coronaria and Malus ioensis genomes and a gene family-based pangenome of native North American apples.DNA research : an international journal for rapid publication of reports on genes and genomes · 2024Article
- Genomic data provides insights into the evolutionary history and adaptive differentiation of two tetraploid strawberries.Horticulture research · 2024Article
- Haplotype-resolved genome assembly for tetraploid Chinese cherry (Horticulture research · 2024Article
6 more citing papers are in PubMed but not listed here.
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Authors and funding
22 authors at 9 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe report an improved assembly and scaffolding of the European pear (Pyrus communis L.) genome (referred to as BartlettDHv2.0), obtained using a combination of Pacific Biosciences RSII long-read sequencing, Bionano optical mapping, chromatin interaction capture (Hi-C), and genetic mapping. The sample selected for sequencing is a double haploid derived from the same "Bartlett" reference pear that was previously sequenced. Sequencing of di-haploid plants makes assembly more tractable in highly heterozygous species such as P. communis.
findingsA total of 496.9 Mb corresponding to 97% of the estimated genome size were assembled into 494 scaffolds. Hi-C data and a high-density genetic map allowed us to anchor and orient 87% of the sequence on the 17 pear chromosomes. Approximately 50% (247 Mb) of the genome consists of repetitive sequences. Gene annotation confirmed the presence of 37,445 protein-coding genes, which is 13% fewer than previously predicted.
conclusionsWe showed that the use of a doubled-haploid plant is an effective solution to the problems presented by high levels of heterozygosity and duplication for the generation of high-quality genome assemblies. We present a high-quality chromosome-scale assembly of the European pear Pyrus communis and demostrate its high degree of synteny with the genomes of Malus x Domestica and Pyrus x bretschneideri.
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