ArticlePain medicine (Malden, Mass.)2020
Prescription Opioid Misuse Motives in US Older Adults.
Article in Pain medicine (Malden, Mass.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 48 citations in OpenAlex.
- Cannabidiol reduces oxycodone self-administration while preserving its analgesic efficacy in a rat model of neuropathic pain.Scientific reports · 2026Article
- From Peak to Plunge: A Multi-Database Analysis of State-Level Disparities in Hydromorphone Use in the US.Pharmacy (Basel, Switzerland) · 2025Article
- Chronic pain selectively reduces the motivation to work for remifentanil but not food reward.Pain · 2025Article
- Unrelieved pain and risk of opioid use disorder or overdose in older adults prescribed opioids.Pain · 2025Article
- Social Withdrawal and Prescription Opioid Misuse Among Older Adults in the United States.Innovation in aging · 2025Article
- Mitigating Sociodemographic Bias in Opioid Use Disorder Prediction: Fairness-Aware Machine Learning Framework.JMIR AI · 2024Article
- Indirect effects of emotion regulation in the relationship between pain and cannabis use in adults 18-64 years.Addictive behaviors · 2024Article
- Predicting first use of heroin from prescription opioid use subtypes: Insights from the Monitoring the Future longitudinal panel.Drug and alcohol dependence · 2024Article
- Pain management in trauma: the need for trauma-informed opioid prescribing guidelines.Trauma surgery & acute care open · 2024Article
- A Lifestyle Risk Reduction Model for Preventing High-Risk Substance Use Across the Lifespan.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Intentional use of both opioids and cocaine in the United States.Preventive medicine reports · 2023Article
- Prescription drug dependence with and without concurrent illicit drug use: a multicenter cross-sectional survey among an addiction treatment seeking population.Frontiers in psychiatry · 2023Article
- Opioid poisoning cases aged 50+ in the 2015-2020 National Poisoning Data System: suspected suicides versus unintentional poisoning and other intentional misuse/abuse.Drug and chemical toxicology · 2022Article
- Pain Severity and Interference and Substance Use Among Community Pharmacy Patients Prescribed Opioids: A Secondary Analysis of the PHARMSCREEN Study.The journal of pain · 2022Article
- Exposure reasons, other substance use, and medical outcomes of poison control center cases aged 50+ involving opioids, 2015-2020.Clinical toxicology (Philadelphia, Pa.) · 2022Article
- Trajectories of Prescription Drug Misuse Among US Adults From Ages 18 to 50 Years.JAMA network open · 2022Article
- Prescribed opioid use is associated with increased all-purpose emergency department visits and hospitalizations in community-dwelling older adults in the United States.Frontiers in psychiatry · 2022Article
- Co-ingestion of prescription drugs and alcohol in US adults aged 50 years or older.Human psychopharmacology · 2021Article
- Sex differences in factors predicting post-treatment opioid use.Addiction (Abingdon, England) · 2021Article
- Cannabis and Prescription Drug Use Among Older Adults With Functional Impairment.American journal of preventive medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesTo evaluate age-based differences in prescription opioid misuse (POM) motives and to evaluate substance use and mental and physical health correlates of POM motive categories in older adults.
designData were from the National Survey on Drug Use and Health (NSDUH), a nationally representative US survey.
settingThe NSDUH is a household survey. SUBJECTS: A total of 5,826 US residents with past-year POM; 415 were 50 years and older (7.1%).
methodsNine POM motives were assessed among those engaged in past-year POM, grouped into three categories: solely physical pain relief, solely non-pain relief, or mixed motives. Prevalence of POM motives were calculated by age group, with logistic models examining age-based differences. Finally, odds of substance use and mental and physical health correlates by motive category were calculated via logistic models in older adults.
resultsPOM motivated solely by physical pain relief increased from 35.1% in young adults to 65.4% in older adults; in older adults, 84.7% of POM episodes involved pain relief as a motive. POM for solely non-pain relief or mixed motives was associated with greater odds, vs pain relief only, of past-year benzodiazepine misuse (odds ratio [OR] = 4.43 and 6.15, respectively), any substance use disorder (OR = 5.57 and 5.60, respectively), and suicidal ideation (OR = 4.05 and 3.56, respectively) in older adults.
conclusions. POM motives change over the lifespan, with increasing POM for pain relief with aging. Comprehensive nonopioid pain management is needed for those engaged in POM for pain relief, and substance use and mental health treatment are needed for those with non-pain relief motives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.