Evidence map›Paper›PMID 31816070›Full record

ArticleHealth policy and planning2019

Inappropriate use of medicines and associated factors in Brazil: an approach from a national household survey.

Vera Lucia Luiza, Luiz Villarinho Pereira Mendes, Noemia Urruth Leão Tavares, Andrea Damaso Bertoldi, Andréia Turmina Fontanella, Maria Auxiliadora Oliveira, Mônica Rodrigues Campos, PNAUM Group

Open access · hybridAbstract read
In one paragraph

Article in Health policy and planning, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Vera Lucia LuizaDepartment of Medicines and Pharmaceutical Policies, National School of Public Health Sergio Arouca, Oswaldo Cruz Foundation, 1480 Rua Leopoldo Bulhões # 624 or 632, Manguinhos, ZC 21041-210, Rio de Janeiro, RJ, Brazil.
Luiz Villarinho Pereira MendesDepartment of Medicines and Pharmaceutical Policies, National School of Public Health Sergio Arouca, Oswaldo Cruz Foundation, 1480 Rua Leopoldo Bulhões # 624 or 632, Manguinhos, ZC 21041-210, Rio de Janeiro, RJ, Brazil.
Noemia Urruth Leão TavaresPharmacy Department, Health Science School, University of Brasília (UnB), Campus Darcy Ribeiro, Asa Norte, Brasilia, DF, 70910-900, Brazil.
Andrea Damaso BertoldiDepartment of Social Medicine, School of Medicine, Postgraduate Program in Epidemiology, Federal University of Pelotas, 1160 Marechal Deodoro Street, Pelotas, RS, 96020-220, Brazil.
Andréia Turmina FontanellaDepartment of Social Medicine, School of Medicine, Federal University of Rio Grande do Sul, 2400 Ramiro Barcelos Street, Porto Alegre, RS, 90.035-003, Brazil.
Maria Auxiliadora OliveiraDepartment of Medicines and Pharmaceutical Policies, National School of Public Health Sergio Arouca, Oswaldo Cruz Foundation, 1480 Rua Leopoldo Bulhões # 624 or 632, Manguinhos, ZC 21041-210, Rio de Janeiro, RJ, Brazil.
Mônica Rodrigues CamposDepartment of Social Sciences, National School of Public Health Sergio Arouca, Oswaldo Cruz Foundation, 1480 Rua Leopoldo Bulhões # 624 or 632, Manguinhos, ZC 21041-210, Rio de Janeiro, RJ, Brazil.
PNAUM Group
Escola Nacional de Saúde Pública · BRUniversidade de Brasília · BRUniversidade Federal de Pelotas · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article aims to describe the inappropriate use of medicines in the Brazilian urban population and to identify associated factors. We conducted a data analysis of a household survey carried out in Brazil in 2013-14. The sampling plan was done by clusters with representativeness of the urban population and large regions of the country, according to gender and age domains. For this analysis, we considered a sample of adults (≥20 years) who reported having chronic non-communicable diseases, medical indication for drug treatment and medicine use (n = 12 283). We evaluated the prevalence of inappropriate use in the domains: non-adherence, inappropriate use behaviour and inadequate care with medicines, all verified in the following groups of independent variables: demographic and socio-economic characteristics, health and pharmaceutical care, health status and use of medicines. Crude and adjusted prevalence ratios were obtained using robust Poisson regression. It was found 46.1% of people having at least one behaviour of inappropriate use of medicines. The worst results were found for the domain of inappropriate use behaviour, a situation of 36.6% of the users, which included unauthorized prescriber, inadequate source of information and indication of the medicines by non-authorized prescribers. The best result was found for the lack of medicines care, informed by only 4.6% of users who kept expired drugs at home. The inappropriate use of medicines was associated with gender (female), region of residence (Northeast), not visiting the doctor regularly or visiting more than one doctor, not having free access to medicines and using of five or more medicines. There was a high prevalence of inappropriate use, which was associated with both individual and health system characteristics pointing out the need to set priorities as for health education and public interventions.

Indexed as

Drug MonitoringAdultBrazilChronic DiseaseDemographyDrug MisuseFamily CharacteristicsFemaleHealth Services AccessibilityHealth StatusHealth SurveysHumansMaleMiddle AgedPrescription DrugsSocioeconomic FactorsPrescription DrugsChronic non-communicable diseaseshousehold surveyprimary health carerational use of medicines

Identifiers

PMID31816070
PMCPMC6901078
OpenAlexW2994926908

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.