Evidence map›Paper›PMID 31816036›Full record

Trial reportJAMA pediatrics2020

Familial Haploidentical Stem Cell Transplant in Children and Adolescents With High-Risk Sickle Cell Disease: A Phase 2 Clinical Trial.

Mitchell S Cairo, Julie-An Talano, Theodore B Moore, Qiuhu Shi, Rona Singer Weinberg, Brenda Grossman, Shalini Shenoy

Open access · bronzeAbstract readClinical Trial, Phase IILetterMulticenter Study
In one paragraph

Trial report in JAMA pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Mitchell S CairoDepartment of Pediatrics, New York Medical College, Valhalla.
Julie-An TalanoDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee.
Theodore B MooreDepartment of Pediatrics, University of California, Los Angeles, Los Angeles.
Qiuhu ShiDepartment of Epidemiology & Community Health, New York Medical College, Valhalla.
Rona Singer WeinbergThe New York Blood Center, New York.
Brenda GrossmanDepartment of Pathology & Immunology, Washington University in St Louis, St Louis, Missouri.
Shalini ShenoyDepartment of Pediatrics, Washington University in St Louis, St Louis, Missouri.
New York Medical College · USWashington University in St. Louis · USMedical College of Wisconsin · USNew York Blood Center · USUniversity of California, Los Angeles · US

Funding

Phase 2 Defibrotide PPX in High Risk SCD Pts w/MAC&Haplo AlloSCT IND127812 9-3-15R01FD004090 · FDA · NEW YORK MEDICAL COLLEGE · PI CAIRO, MITCHELL S. · 2012 to 2020
$3.3M
FDA HHS R01 FD004090
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Stem Cell TransplantationAdolescentAnemia, Sickle CellChildChild, PreschoolFemaleHumansMaleProspective StudiesRisk AssessmentYoung Adult

Identifiers

PMID31816036
PMCPMC6902105
OpenAlexW2993155999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.