ArticleReproductive biology and endocrinology : RB&E2019
Semen quality pattern and age threshold: a retrospective cross-sectional study of 71,623 infertile men in China, between 2011 and 2017.
Article in Reproductive biology and endocrinology : RB&E, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 49 citations in OpenAlex.
- Influence of age on sperm characteristics evaluated by light and electron microscopies.Scientific reports · 2021Trial
- Association between body mass index and semen quality in infertile men: a cross-sectional study of 28 167 patients.Asian journal of andrology · 2026Article
- Construction and Validation of a Clinical Pregnancy Outcome Prediction Model for Infertility Treatment Using IVF/ICSI: A Retrospective Study Based on 11,449 Cases.Frontiers in endocrinology · 2026Article
- Epidemiological characteristics and temporal trends of male infertility in Egypt (2012-2022): Analysis of 3,037 consecutive cases.Arab journal of urology · 2026Article
- Molecular weight-based profiling of sperm proteins and their association with semen quality in Kokok Balenggek roosters.Journal of advanced veterinary and animal research · 2025Article
- Ambient air pollution during developmental windows of spermatogenesis and semen quality among an infertility treatment seeking population.Ecotoxicology and environmental safety · 2025Article
- Identifying critical windows of air pollution exposure and semen quality: A cross-sectional study in Chinese fertile men.BMC public health · 2025Article
- High-Coverage UHPLC-MS/MS Analysis of 67 Mycotoxins in Plasma for Male Infertility Exposure Studies.Toxics · 2024Article
- Y chromosome microdeletions in Chinese men with infertility: prevalence, phenotypes, and intracytoplasmic sperm injection outcomes.Reproductive biology and endocrinology : RB&E · 2023Article
- Improved sperm DNA fragmentation levels in infertile men following very short abstinence of 3-4 hours.Translational andrology and urology · 2023Article
- Geographic Differences in Semen Quality among a Cohort of American Men Using Mail-in Sperm Testing Kits.The world journal of men's health · 2023Article
- Changes in Semen Analysis over Time: A Temporal Trend Analysis of 20 Years of Subfertile Non-Azoospermic Men.The world journal of men's health · 2023Article
- Unboxing Industry-Standard AI Models for Male Fertility Prediction with SHAP.Healthcare (Basel, Switzerland) · 2023Article
- Trends in sperm quality by computer-assisted sperm analysis of 49,189 men during 2015-2021 in a fertility center from China.Frontiers in endocrinology · 2023Article
- The effect of aging on semen parameters in normozoospermic men: A cross-sectional study.International journal of reproductive biomedicine · 2022Article
- Spatiotemporal trends in human semen quality.Nature reviews. Urology · 2022Review
- Pattern of semen analysis in male partners of infertile couples in Western Ethiopia: Retrospective cross-sectional study.SAGE open medicine · 2022Article
- Do aging, drinking, and having unhealthy weight have a synergistic impact on semen quality?Journal of assisted reproduction and genetics · 2021Article
- Research Progress on the Relationship between Obesity-Inflammation-Aromatase Axis and Male Infertility.Oxidative medicine and cellular longevity · 2021Review
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe aim of this study was to provide information on the semen quality pattern of infertile men and age thresholds for semen parameters in China.
methodsThis was a retrospective cross-sectional study investigating 71,623 infertile men from the Reproductive and Genetic Hospital of CITIC Xiangya in Hunan, China, from 2011 to 2017. The Kruskal-Wallis test, Mann-Kendall test, linear regression model and joinpoint regression were used.
resultsAlthough erratic changes were observed in the median semen parameters (sperm concentration 40.1-52.1 × 10
conclusionsThere is no evidence of a deterioration in semen quality among infertile men in Hunan, China. Semen parameters decreased with increasing age, with turning points noted at different ages. Semen parameters are not absolute evidence for the assessment of male fertility potential. Therefore, we believe that, among semen parameters, the sperm concentration is the best predictor of fertility for ART, followed by motility. Decreased sperm motility may affect natural pregnancy, but it is not necessary for successful IVF.
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