ArticleJournal of natural products2019
The DESIGNER Approach Helps Decipher the Hypoglycemic Bioactive Principles of
Article in Journal of natural products, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Regional variation in total flavonoid content and antioxidant activity of Artemisia dracunculus L. in Xinjiang, China.BMC plant biology · 2026Article
- The Evolution of Science and Regulation of Dietary Supplements: Past, Present, and Future.The Journal of nutrition · 2024Review
- Extract ofInternational journal of molecular sciences · 2023Article
- Artemisia Species with High Biological Values as a Potential Source of Medicinal and Cosmetic Raw Materials.Molecules (Basel, Switzerland) · 2022Review
- Article
- Selective Preparation and High Dynamic-Range Analysis of Cannabinoids in "CBD Oil" and OtherJournal of natural products · 2022Article
- Bioactive compounds from Artemisia dracunculus L. activate AMPK signaling in skeletal muscle.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021Article
- Prenylated Coumaric Acids fromJournal of natural products · 2021Article
- Characterization of PMI-5011 on the Regulation of Deubiquitinating Enzyme Activity in Multiple Myeloma Cell Extracts.Biochemical engineering journal · 2021Article
- Designing a Clinical Study With Dietary Supplements: It's All in the Details.Frontiers in nutrition · 2021Article
- Review
- Selective Chlorophyll Removal Method to "Degreen" Botanical Extracts.Journal of natural products · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Complementing classical drug discovery, phytochemicals act on multiple pharmacological targets, especially in botanical extracts, where they form complex bioactive mixtures. The reductionist approach used in bioactivity-guided fractionation to identify single bioactive phytochemicals is inadequate for capturing the full therapeutic potential of the (bio)chemical interactions present in such complex mixtures. This study used a DESIGNER (Deplete and Enrich Select Ingredients to Generate Normalized Extract Resources) approach to selectively remove the known bioactives, 4'-
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.