Evidence map›Paper›PMID 31815440›Full record

ArticleAnalytical chemistry2020

YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA.

Xiaoxia Dai, Gwendolyn Gonzalez, Lin Li, Jie Li, Changjun You, Weili Miao, Junchi Hu, Lijuan Fu, Yonghui Zhao, Ruidong Li and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 99 citations in OpenAlex.

  1. Review
  2. Review
  3. The mJournal of virology · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (mThe Journal of biological chemistry · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. The emerging role of mFrontiers in immunology · 2026
    Review
  13. Review
  14. Review
  15. Advances in RNA modification in myocardial fibrosis (Review).International journal of molecular medicine · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Xiaoxia DaiDepartment of Chemistry , University of California , Riverside , California 92521-0403 , United States.
Gwendolyn GonzalezEnvironmental Toxicology Graduate Program , University of California , Riverside , California 92521-0403 , United States.
Lin LiDepartment of Chemistry , University of California , Riverside , California 92521-0403 , United States.
Jie LiFudan University Shanghai Cancer Center, Department of Oncology; and Institutes of Biomedical Sciences and School of Basic Medical Sciences , Shanghai Medical College of Fudan University , Shanghai 200032 , China.
Changjun YouDepartment of Chemistry , University of California , Riverside , California 92521-0403 , United States.
Weili MiaoDepartment of Chemistry , University of California , Riverside , California 92521-0403 , United States.
Junchi HuDrug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica , Chinese Academy of Sciences , Shanghai 201203 , China.
Lijuan FuEnvironmental Toxicology Graduate Program , University of California , Riverside , California 92521-0403 , United States.
Yonghui ZhaoDepartment of Botany and Plant Sciences, Institute of Integrative Genome Biology , University of California , Riverside , California 92521-0403 , United States.
Ruidong LiDepartment of Cell Biology and Neuroscience , University of California , Riverside , California 92521-0403 , United States.
Lichao LiDepartment of Cell Biology and Neuroscience , University of California , Riverside , California 92521-0403 , United States.
Xuemei ChenDepartment of Botany and Plant Sciences, Institute of Integrative Genome Biology , University of California , Riverside , California 92521-0403 , United States.
Yanhui XuFudan University Shanghai Cancer Center, Department of Oncology; and Institutes of Biomedical Sciences and School of Basic Medical Sciences , Shanghai Medical College of Fudan University , Shanghai 200032 , China.
Weifeng GuDepartment of Cell Biology and Neuroscience , University of California , Riverside , California 92521-0403 , United States.
Yinsheng WangDepartment of Chemistry , University of California , Riverside , California 92521-0403 , United States.ORCID 0000-0001-5565-283X
University of California, Riverside · USShanghai Medical College of Fudan University · CNChinese Academy of Sciences · CN

Funding

Research Training in Environmental ToxicologyT32ES018827 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Yinsheng Wang · 2010 to 2026
$5.3M
Repair and Biological Consequences of Alkylated Thymidine LesionsR01ES025121 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI WANG, YINSHENG · 2015 to 2019
$2.2M
A Novel RNA Polyphosphatase PIR-1 Plays Important Roles in Silencing Viruses and Regulating Genes in C. elegansR01GM124349 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI GU, WEIFENG · 2018 to 2022
$1.8M
NIEHS NIH HHS R01 ES025121NIEHS NIH HHS T32 ES018827NIGMS NIH HHS R01 GM124349
6 · The paper itself

Abstract

5-Methylcytosine is found in both DNA and RNA; although its functions in DNA are well established, the exact role of 5-methylcytidine (m

Indexed as

5-MethylcytosineBinding SitesCells, CulturedHEK293 CellsHeLa CellsHumansMethylationMolecular StructureRNA-Binding ProteinsRNA Processing, Post-TranscriptionalRNA, Ribosomal5-MethylcytosineRNA-Binding ProteinsRNA, RibosomalYTHDF2 protein, human

Identifiers

PMID31815440
PMCPMC6949395
OpenAlexW2995213716

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.