Evidence map›Paper›PMID 31815324›Full record

ArticleMagnetic resonance in medicine2020

Imaging the distribution of iron oxide nanoparticles in hypothermic perfused tissues.

Hattie L Ring, Zhe Gao, Anirudh Sharma, Zonghu Han, Charles Lee, Kelvin G M Brockbank, Elizabeth D Greene, Kristi L Helke, Zhen Chen, Lia H Campbell and 9 more

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Histochemistry for nanomedicine: Novelty in tradition.European journal of histochemistry : EJH · 2021
    Article
  5. Vitrification and Nanowarming of Kidneys.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Hattie L RingCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0001-5779-2561
Zhe GaoDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, Minnesota.
Anirudh SharmaDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, Minnesota.
Zonghu HanDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, Minnesota.
Charles LeeDepartment of Mechanical Engineering and Engineering Science, University of North Carolina, Charlotte, North Carolina.
Kelvin G M BrockbankTissue Testing Technologies LLC, North Charleston.
Elizabeth D GreeneTissue Testing Technologies LLC, North Charleston.
Kristi L HelkeDepartment of Comparative Medicine, Medical University of South Carolina, Charleston, South Carolina.
Zhen ChenTissue Testing Technologies LLC, North Charleston.
Lia H CampbellTissue Testing Technologies LLC, North Charleston.
Bradley WeegmanSylvatica Biotech, Inc., North Charleston, South Carolina.
Monica DavisSylvatica Biotech, Inc., North Charleston, South Carolina.
Michael TaylorSylvatica Biotech, Inc., North Charleston, South Carolina.
Sebastian GiwaSylvatica Biotech, Inc., North Charleston, South Carolina.
Gregory M Fahy21st Century Medicine, Inc., Fontana, California.
Brian Wowk21st Century Medicine, Inc., Fontana, California.
Roberto Pagotan21st Century Medicine, Inc., Fontana, California.
John C BischofDepartment of Mechanical Engineering, University of Minnesota, Minneapolis, Minnesota.
Michael GarwoodCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota.
University of Minnesota · US21st Century Medicine (United States) · USApplied Tissue Technologies (United States) · USMedical University of South Carolina · USUniversity of North Carolina at Charlotte · US

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Mehmet Akcakaya · 2019 to 2026
$11.7M
NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
Organ banking for transplant—kidney cryopreservation by vitrification and novel nanowarming technologyR01DK117425 · NIDDK · UNIVERSITY OF MINNESOTA · PI JOHN C BISCHOF, Erik Brian Finger · 2018 to 2026
$4.9M
Breakthrough Tissue and Organ Preservation and Transplantation Using Scaled-Up Nanowarming TechnologyR01HL135046 · NHLBI · UNIVERSITY OF MINNESOTA · PI BISCHOF, JOHN C, FINGER, ERIK BRIAN · 2017 to 2020
$2.6M
NHLBI NIH HHS R01 HL135046NIBIB NIH HHS P41 EB015894NIBIB NIH HHS P41 EB027061NIDDK NIH HHS R01 DK117425
6 · The paper itself

Abstract

purposeHerein, we evaluate the use of MRI as a tool for assessing iron oxide nanoparticle (IONP) distribution within IONP perfused organs and vascularized composite allografts (VCAs) (i.e., hindlimbs) prepared for cryopreservation.

methodsMagnetic resonance imaging was performed on room-temperature organs and VCAs perfused with IONPs and were assessed at 9.4 T. Quantitative T

resultsQuantitative imaging was achieved for organs and VCAs perfused with up to 642 mM

conclusionUsing MRI, we were able to assess the distribution of IONPs throughout organs and VCAs varying in complexity. Additional studies are necessary to better understand this system and validate the calibration between T

Indexed as

Magnetite NanoparticlesNanoparticlesAnimalsFerric CompoundsMagnetic Iron Oxide NanoparticlesMagnetic Resonance ImagingStaining and LabelingFerric CompoundsMagnetite Nanoparticlesandcryopreservationiron oxide nanoparticleMRInanowarmingorgan preservationSWIFTT1T2

Identifiers

PMID31815324
PMCPMC6982566
OpenAlexW2994410115

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.