ArticleACS omega2019
Single Polar Cell Trapping Based on the Breath Figure Method.
Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Metabolic heterogeneity in early-stage lung adenocarcinoma revealed by RNA-seq and scRNA-seq.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to research individual cells is important for various biological studies. Currently reported biointerfaces for single-cell analysis can only trap individual cells in random morphologies. Cell polarity is a key factor in cellular functions, and the study of single-cell polarity can facilitate an understanding of cancer metastasis and stem-cell differentiation. For single polar cell trapping, anisotropic honeycomb-structured films were prepared. Elastic poly(1,2-butadiene) honeycomb films with ordered hexagonal pores were first prepared via the breath figure method. Subsequently, the films were subjected to mechanical stretching and fixed via photo-cross-linking under UV light irradiation. This stretched honeycomb structure was then transferred to a polystyrene surface. The resultant anisotropic porous films exhibited excellent capacity for single-cell trapping. Besides contributing to the physical spatial confinement of cells, the trapped single cells exhibited orientation in different polarities. The single polar cell array provided a novel platform for fundamental biological research.
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Registered trials
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