Evidence map›Paper›PMID 31815088›Full record

ArticleGMS infectious diseases2019

TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection.

Benedikt C Buerfent, Jesuthas Ajendra, Wiebke Stamminger, Fabian Gondorf, Achim Hoerauf, Marc P Hübner

Open access · greenAbstract read
In one paragraph

Article in GMS infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Benedikt C BuerfentInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany.
Jesuthas AjendraInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany.
Wiebke StammingerInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany.
Fabian GondorfInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany.
Achim HoeraufInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany.
Marc P HübnerInstitute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Germany.
University Hospital Bonn · DELife & Brain (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TGFβ is an anti-inflammatory molecule that suppresses pro-inflammatory immune responses. Previously, we demonstrated that chronic filarial infection has a beneficial impact on

Indexed as

E. colifilariahelminthimmune modulationLitomosoides sigmodontisnematodesepsissystemic pro-inflammatory response syndrome (SIRS)TGF beta

Identifiers

PMID31815088
PMCPMC6883344
OpenAlexW2996332066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.