Evidence map›Paper›PMID 31814995›Full record

ArticleCell discovery2019

Efficient base editing with expanded targeting scope using an engineered Spy-mac Cas9 variant.

Zhiquan Liu, Huanhuan Shan, Siyu Chen, Mao Chen, Yuning Song, Liangxue Lai, Zhanjun Li

Abstract read
In one paragraph

Article in Cell discovery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Efforts to Downsize Base Editors for Clinical Applications.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Review
  4. Base editing enables duplex point mutagenesis inFrontiers in bioengineering and biotechnology · 2023
    Article
  5. CRISPR technologies for the treatment of Duchenne muscular dystrophy.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Current Status and Challenges of DNA Base Editing Tools.Molecular therapy : the journal of the American Society of Gene Therapy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiquan Liu *1Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Science, Jilin University, 130062 Changchun, China.
Huanhuan Shan *1Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Science, Jilin University, 130062 Changchun, China.
Siyu Chen1Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Science, Jilin University, 130062 Changchun, China.
Mao Chen1Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Science, Jilin University, 130062 Changchun, China.
Yuning Song1Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Science, Jilin University, 130062 Changchun, China.
Liangxue Lai1Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Science, Jilin University, 130062 Changchun, China.
Zhanjun Li1Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Science, Jilin University, 130062 Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA recombinationGenomic analysis

Identifiers

PMID31814995
PMCPMC6888851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.