Evidence map›Paper›PMID 31814981›Full record

ArticleMolecular and clinical oncology2020

Quantitative assessment of radiodermatitis through a non-invasive objective procedure in patients with breast cancer.

Maiko Kitajima, Kasumi Mikami, Yuka Noto, Chieko Itaki, Yasuyo Fukushi, Yoshiko Hirota, Yasushi Mariya, Megumi Tsushima, Keiichi Kattou, Tomohiro Osanai

Abstract read
In one paragraph

Article in Molecular and clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Radiation dermatitis assessment tools used in breast cancer: A systematic review of measurement properties.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Comparison of clinical practice guidelines on radiation dermatitis: a narrative review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maiko KitajimaDepartment of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Aomori 036-8564, Japan.
Kasumi MikamiDepartment of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Aomori 036-8564, Japan.
Yuka NotoDepartment of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Aomori 036-8564, Japan.
Chieko ItakiDepartment of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Aomori 036-8564, Japan.
Yasuyo FukushiDepartment of Radiology, Mutsu General Hospital, Mutsu, Aomori 035-8601, Japan.
Yoshiko HirotaHirosaki Central Hospital, Hirosaki, Aomori 036-8188, Japan.
Yasushi MariyaDepartment of Radiology, Mutsu General Hospital, Mutsu, Aomori 035-8601, Japan.
Megumi TsushimaDepartment of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Aomori 036-8564, Japan.
Keiichi KattouHirosaki Central Hospital, Hirosaki, Aomori 036-8188, Japan.
Tomohiro OsanaiDepartment of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Aomori 036-8564, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Assessment of skin condition is necessary for providing advice regarding skin self-care to patients with breast cancer who have undergone radiation therapy. Acute and chronic phases of radiodermatitis were analyzed in patients using objective assessment tools in the present study. A total of 18 women who received radiation therapy for breast cancer were enrolled in the present study and their skin surface temperature (SST), hydration level of the skin surface (HL), melanin intensity (MI) and erythema intensity (EI) were measured prior to radiation therapy and six months thereafter. Furthermore, skin condition was assessed using the Common Terminology Criteria for Adverse Events (CTCAE). EI and MI levels at the irradiated site peaked upon the completion of radiation therapy and declined to baseline at 6 months. In contrast, SST levels were elevated at the irradiated site during radiation therapy (P<0.05) and plateaued after its completion. The same parameters in non-irradiated control sites remained unchanged during the study period. HL reached the minimum in irradiated and non-irradiated sites upon completion of radiation therapy. Although HL returned to baseline in the non-irradiated site 6 months after radiation therapy, it remained low in the irradiated site. No relationship between the CTCAE and EI level was observed. In conclusion, the present study demonstrated that objective assessment tools, including SST and EI levels, were useful for assessing skin condition during radiodermatitis. The combination of the CTCAE and objective assessment tools will enable a more accurate assessment of radiodermatitis.

Indexed as

breast cancererythema intensityhydration levelradiodarmatitisskin surface temperature

Identifiers

PMID31814981
PMCPMC6888041

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.