Evidence map›Paper›PMID 31814881›Full record

ArticleOxidative medicine and cellular longevity2019

miR-185 and SEPT5 Genes May Contribute to Parkinson's Disease Pathophysiology.

Arman Rahimmi, Ilaria Peluso, Aref Rajabi, Kambiz Hassanzadeh

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. MicroRNAs and synaptic dysfunction in Parkinson's disease.Molecular therapy. Nucleic acids · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Arman RahimmiStudent Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.ORCID https://orcid.org/0000-0003-0720-3487
Ilaria PelusoCouncil for Agricultural Research and Economics, Research Centre for Food and Nutrition (CREA-AN), Via Ardeatina 546, 00178 Rome, Italy.ORCID https://orcid.org/0000-0002-6210-5241
Aref RajabiDepartment of Neurology, Kurdistan University of Medical Sciences, Sanandaj, Iran.ORCID https://orcid.org/0000-0001-6909-1420
Kambiz HassanzadehCellular and Molecular Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.ORCID https://orcid.org/0000-0002-8737-312X
Kurdistan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are still unknown mechanisms involved in the development of Parkinson's disease (PD), which elucidating them can assist in developing efficient therapies. Recently, studies showed that genes located on the human chromosomal location 22q11.2 might be involved in the development of PD. Therefore, the present study was designed to evaluate the role of two genes located on the chromosomal location (miR-185 and SEPT5), which were the most probable candidates based on our bibliography.

Indexed as

AgedAnimalsCell Cycle ProteinsCell Line, TumorCorpus StriatumDisease Models, AnimalGene ExpressionHumansMaleMicroRNAsParkinson DiseaseRatsRats, WistarRotenoneSeptinsSubstantia NigraCell Cycle ProteinsMicroRNAsMIRN185 microRNA, humanMIRN185 microRNA, ratRotenoneSEPTIN5 protein, humanSeptin5 protein, ratSeptins

Identifiers

PMID31814881
PMCPMC6878792
OpenAlexW2984154152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.