Evidence map›Paper›PMID 31814876›Full record

ArticleOxidative medicine and cellular longevity2019

A Bioinformatic Approach for the Identification of Molecular Determinants of Resistance/Sensitivity to Cancer Thermotherapy.

Mustafa Barbaros Düzgün, Konstantinos Theofilatos, Alexandros G Georgakilas, Athanasia Pavlopoulou

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Mustafa Barbaros DüzgünIzmir Biomedicine and Genome Center (IBG), 35340 Balcova, Izmir, Turkey.ORCID https://orcid.org/0000-0002-7385-1004
Konstantinos TheofilatosInSyBio Ltd, Innovations House, 19 Staple Gardens, Winchester, SO23 8SR, UK.ORCID https://orcid.org/0000-0001-6799-0553
Alexandros G GeorgakilasDNA Damage Laboratory, Physics Department, School of Applied Mathematical and Physical Sciences, National Technical University of Athens, Iroon Polytechniou 9, 15780 Zografou, Greece.ORCID https://orcid.org/0000-0002-5971-0010
Athanasia PavlopoulouIzmir Biomedicine and Genome Center (IBG), 35340 Balcova, Izmir, Turkey.ORCID https://orcid.org/0000-0002-0815-3808
Dokuz Eylül University · TRCN Bio Innovations (United Kingdom) · GBNational Technical University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Application of heat above 43°C and up to 47°C, the so-called "thermal ablation" range, leads to tumor cell destruction either by apoptosis or by necrosis. However, tumor cells have developed mechanisms of defense that render them thermoresistant. Of importance, the

Indexed as

Computational BiologyGene ExpressionHigh-Throughput Screening AssaysHumansHyperthermia, InducedNeoplasmsSurvival Analysis

Identifiers

PMID31814876
PMCPMC6878812
OpenAlexW2987196402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.