Evidence map›Paper›PMID 31814871›Full record

ArticleOxidative medicine and cellular longevity2019

Astrocyte-Targeted Transporter-Utilizing Derivatives of Ferulic Acid Can Have Multifunctional Effects Ameliorating Inflammation and Oxidative Stress in the Brain.

Ahmed Montaser, Johanna Huttunen, Sherihan Abdelhamid Ibrahim, Kristiina M Huttunen

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ahmed MontaserSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.
Johanna HuttunenSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.
Sherihan Abdelhamid IbrahimDepartment of Pharmacology and Therapeutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University, 21311 Alexandria, Egypt.
Kristiina M HuttunenSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.ORCID https://orcid.org/0000-0002-1175-8517
University of Eastern Finland · FIPharos University in Alexandria · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferulic acid (FA) is a natural phenolic antioxidant, which can exert also several other beneficial effects to combat neuroinflammation and neurodegenerative diseases, such as Alzheimer's disease. One of these properties is the inhibition of several enzymes and factors, such as

Indexed as

Amino Acid Transport System y+LAnimalsAnti-Inflammatory Agents, Non-SteroidalAstrocytesBrainCoumaric AcidsEncephalitisHumansLarge Neutral Amino Acid-Transporter 1MCF-7 CellsMice, Inbred C57BLMice, TransgenicMolecular Targeted TherapyOxidative StressAmino Acid Transport System y+LAnti-Inflammatory Agents, Non-SteroidalCoumaric Acidsferulic acidLarge Neutral Amino Acid-Transporter 1SLC7A5 protein, humanSlc7a7 protein, mouse

Identifiers

PMID31814871
PMCPMC6877910
OpenAlexW2984874217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.