Evidence map›Paper›PMID 31814866›Full record

ArticleOxidative medicine and cellular longevity2019

Giacomo Pepe, Manuela Giovanna Basilicata, Albino Carrizzo, Simona Adesso, Carmine Ostacolo, Marina Sala, Eduardo Sommella, Marco Ruocco, Stella Cascioferro, Mariateresa Ambrosio and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Antitumor Mechanisms ofLife (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Giacomo PepeDepartment of Pharmacy, University of Salerno, Fisciano, Italy.ORCID https://orcid.org/0000-0002-7561-2023
Manuela Giovanna BasilicataDepartment of Pharmacy, University of Salerno, Fisciano, Italy.
Albino CarrizzoIRCCS Neuromed, Loc. Camerelle, Pozzilli, Italy.ORCID https://orcid.org/0000-0003-2689-0008
Simona AdessoDepartment of Pharmacy, University of Salerno, Fisciano, Italy.
Carmine OstacoloDepartment of Pharmacy, University of Naples Federico II, NA, Italy.
Marina SalaDepartment of Pharmacy, University of Salerno, Fisciano, Italy.ORCID https://orcid.org/0000-0003-2739-7215
Eduardo SommellaDepartment of Pharmacy, University of Salerno, Fisciano, Italy.
Marco RuoccoDepartment of Pharmacy, University of Salerno, Fisciano, Italy.
Stella CascioferroDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche (STEBICEF), University of Palermo, PA, Italy.
Mariateresa AmbrosioIRCCS Neuromed, Loc. Camerelle, Pozzilli, Italy.
Simona PisantiDepartment of Medicine and Surgery, University of Salerno, Baronissi, Italy.
Veronica Di SarnoDepartment of Pharmacy, University of Salerno, Fisciano, Italy.
Alessia BertaminoDepartment of Pharmacy, University of Salerno, Fisciano, Italy.
Stefania MarzoccoDepartment of Pharmacy, University of Salerno, Fisciano, Italy.ORCID https://orcid.org/0000-0003-2333-1630
Carmine VecchioneIRCCS Neuromed, Loc. Camerelle, Pozzilli, Italy.
Pietro CampigliaDepartment of Pharmacy, University of Salerno, Fisciano, Italy.ORCID https://orcid.org/0000-0002-1069-2181
University of Salerno · ITIstituto Neurologico Mediterraneo · ITUniversity of Naples Federico II · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptides derived from buffalo dairy products possess multiple healthy properties that cannot be exerted as long as they are encrypted in parent proteins. To evaluate the biological activities of encrypted peptide sequences from buffalo ricotta cheese, we performed a simulated gastrointestinal (GI) digestion. Chemical and pharmacological characterization of the digest led to the identification of a novel peptide endowed with antioxidant and antihypertensive action. The GI digest was fractionated by Semiprep-HPLC, and fractions were tested against reactive oxygen species (ROS) release in an H

Indexed as

Angiotensin IIAnimalsAntioxidantsCaco-2 CellsEpithelial CellsHumansIntestinal MucosaLactoglobulinsMesenteric ArteriesMiceNF-E2-Related Factor 2Oxidative StressPeptide FragmentsRatsReactive Oxygen SpeciesVasoconstrictionAngiotensin IIAntioxidantsLactoglobulinsNfe2l2 protein, mouseNF-E2-Related Factor 2Peptide FragmentsReactive Oxygen Species

Identifiers

PMID31814866
PMCPMC6877959
OpenAlexW2986763958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.