Evidence map›Paper›PMID 31814812›Full record

ArticleEJIFCC2019

Flow Cytometric Analysis of Monocytes Polarization and Reprogramming From Inflammatory to Immunosuppressive Phase During Sepsis.

Marilena Greco, Aurora Mazzei, Claudio Palumbo, Tiziano Verri, Giambattista Lobreglio

Open access · greenAbstract read
In one paragraph

Article in EJIFCC, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The Modulation of Septic Shock: A Proteomic Approach.International journal of molecular sciences · 2024
    Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Decrease of Non-Classical and Intermediate Monocyte Subsets in Severe Acute SARS-CoV-2 Infection.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marilena GrecoClinical Pathology and Microbiology Laboratory, Vito Fazzi General Hospital ASL-Lecce, Lecce, Italy.
Aurora MazzeiLaboratory of Physiology, Department of Biological and Environmental Sciences and Technologies (DeBEST), University of Salento, Lecce, Italy.
Claudio PalumboClinical Pathology and Microbiology Laboratory, Vito Fazzi General Hospital ASL-Lecce, Lecce, Italy.
Tiziano VerriLaboratory of Physiology, Department of Biological and Environmental Sciences and Technologies (DeBEST), University of Salento, Lecce, Italy.
Giambattista LobreglioClinical Pathology and Microbiology Laboratory, Vito Fazzi General Hospital ASL-Lecce, Lecce, Italy.
Ospedale Vito Fazzi · ITUniversity of Salento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis outcome is determined by a balance between inflammation and immune suppression. We aimed to evaluate monocytes polarization and reprogramming during these processes. We analyzed 93 patients with procalcitonin level >0.5 ng/mL (hPCT) and suspected/confirmed sepsis, and 84 controls by analysis of CD14, CD16 and HLA-DR expression on blood monocytes using fluorescent labeled monoclonal antibodies and BD FACS CANTO II. Complete blood cell count, procalcitonin and other biochemical markers were evaluated. Intermediate monocytes CD14

Indexed as

flow cytometryimmune-paralysismonocytes

Identifiers

PMID31814812
PMCPMC6893894
OpenAlexW2995445771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.