Evidence map›Paper›PMID 31814772›Full record

ArticleClinical epidemiology2019

The End Rheumatic Heart Disease in Australia Study of Epidemiology (ERASE) Project: data sources, case ascertainment and cohort profile.

Judith M Katzenellenbogen, Daniela Bond-Smith, Rebecca J Seth, Karen Dempsey, Jeffrey Cannon, Lee Nedkoff, Frank M Sanfilippo, Nicholas de Klerk, Joe Hung, Elizabeth Geelhoed and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Valve biology and rheumatic heart disease pathogenesis.Nature cardiovascular research · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. The "Cairo Accord"- Towards the Eradication of RHD: An Update.Frontiers in cardiovascular medicine · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Case Ascertainment on Australian Registers for Acute Rheumatic Fever and Rheumatic Heart Disease.International journal of environmental research and public health · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Judith M Katzenellenbogen *School of Population and Global Health, The University of Western Australia, Perth, WA, Australia.
Daniela Bond-Smith *School of Population and Global Health, The University of Western Australia, Perth, WA, Australia.
Rebecca J SethSchool of Population and Global Health, The University of Western Australia, Perth, WA, Australia.ORCID 0000-0002-3551-6205
Karen DempseyGlobal and Tropical Health, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia.ORCID 0000-0001-8901-8669
Jeffrey CannonGroup A Streptococcus Research Group, Telethon Kids Institute, Perth, WA, Australia.
Lee NedkoffSchool of Population and Global Health, The University of Western Australia, Perth, WA, Australia.
Frank M SanfilippoSchool of Population and Global Health, The University of Western Australia, Perth, WA, Australia.ORCID 0000-0003-3639-0787
Nicholas de KlerkSchool of Population and Global Health, The University of Western Australia, Perth, WA, Australia.ORCID 0000-0001-9223-0767
Joe HungSchool of Population and Global Health, The University of Western Australia, Perth, WA, Australia.ORCID 0000-0002-4468-6097
Elizabeth GeelhoedSchool of Allied Health, The University of Western Australia, Perth, WA, Australia.
Daniel WilliamsonAboriginal and Torres Strait Islander Health Branch, Queensland Health, Brisbane, QLD, Australia.
Rosemary WyberGroup A Streptococcus Research Group, Telethon Kids Institute, Perth, WA, Australia.
Anna P RalphGlobal and Tropical Health, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia.ORCID 0000-0002-2253-5749
Dawn BessarabSchool of Population and Global Health, The University of Western Australia, Perth, WA, Australia.ORCID 0000-0002-9716-1593
ERASE Collaboration Study Group
The University of Western Australia · AUThe Kids Research Institute Australia · AUCharles Darwin University · AUQueensland Health · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcute rheumatic fever (ARF) and rheumatic heart disease (RHD) persist as public health issues in developing countries and among disadvantaged communities in high-income countries, with rates in Aboriginal and Torres Strait Islander peoples in Australia among the highest recorded globally. A robust evidence base is critical to support policy recommendations for eliminating RHD, but available data are fragmented and incomplete. The End RHD in Australia: Study of Epidemiology (ERASE) Project aims to provide a comprehensive database of ARF and RHD cases in Australia as a basis for improved monitoring and to assess prevention and treatment strategies. The objective of this paper is to describe the process for case ascertainment and profile of the study cohort. PATIENTS AND

methodsThe ERASE database has been built using linked administrative data from RHD registers, inpatient hospitalizations, and death registry data from 2001 to 2017 (mid-year). Additional linked datasets are available. The longitudinal nature of the data is harnessed to estimate onset and assess the progression of the disease. To accommodate systematic limitations in diagnostic coding for RHD, hospital-only identified RHD has been determined using a purposefully developed prediction model.

resultsOf 132,053 patients for whom data were received, 42,064 are considered true cases of ARF or RHD in the study period. The patient population under 60 years in the compiled dataset is more than double the number of patients identified in ARF/RHD registers (12,907 versus 5049). Non-registered patients were more likely to be older, non-Indigenous, and at a later disease stage.

conclusionThe ERASE Project has created an unprecedented linked administrative database on ARF and RHD in Australia. These data provide a critical baseline for efforts to end ARF/RHD in Australia. The methodological work conducted to compile this database resulted in significant improvements in the robustness of epidemiological estimates and entails valuable lessons for ARF/RHD research globally.

Indexed as

epidemiologyindigenouslinked datarheumatic feverrheumatic heart disease

Identifiers

PMID31814772
PMCPMC6863132
OpenAlexW2983246109

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.