Evidence map›Paper›PMID 31814768›Full record

ArticleCancer management and research2019

Prognostic Value Of The Preoperative Neutrophil To Lymphocyte Ratio In Patients With Sinonasal Squamous Cell Carcinoma.

Bing Zhong, Di Deng, Jin-Tao Du, Fei Chen, Ya-Feng Liu, Shi-Xi Liu

Abstract read
In one paragraph

Article in Cancer management and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Prognostic Significance of the Pretreatment Neutrophil-to-Lymphocyte Ratio and Tumor-Associated Neutrophils in Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta-Analysis.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026
    Pooled it
  2. Pre-treatment neutrophil-to-lymphocyte ratio is an independent prognostic factor in head and neck squamous cell carcinoma: Meta-analysis and trial sequential analysis.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bing ZhongDepartment of Otorhinolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Di DengDepartment of Otorhinolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Jin-Tao DuDepartment of Otorhinolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Fei ChenDepartment of Otorhinolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China.ORCID 0000-0002-1948-2711
Ya-Feng LiuDepartment of Otorhinolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Shi-Xi LiuDepartment of Otorhinolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China.ORCID 0000-0003-4573-5695

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study explored the effectiveness of a new inflammatory prognostic system, using preoperative neutrophil to lymphocyte ratio (NLR) to predict the postoperative survival rate of patients with sinonasal squamous cell carcinoma (SSCC).

methodsPatients diagnosed with SSCC who undergone surgically treated without neoadjuvant therapy were included in the study between May 2008 and October 2017. Preoperative NLR is defined as: preoperative neutrophil/postoperative lymphocyte ratio. The prognostic value was uncovered by univariate and multivariate Cox hazards analysis.

resultsA total of 147 patients were included in this study. Through the multivariate analysis, pathological T stage (hazard ratio [HR] 1.719, confidence interval [CI] 1.277-3.642, p<0.001), pathological N stage (HR 1.344, 95% CI 1.015-2.776, p<0.001), and preoperative NLR (HR 1.579, 95% CI 1.217-3.092, p=0.002) were independent risk factor for overall survival (OS). Pathological T stage (HR 1.835, 95% CI 1.141-3.132, <0.001), pathological N stage (HR 1.281, 95% CI 1.169-2.476, p<0.001), and preoperative NLR (HR 1.688, 95% CI 1.162-3.363, p p<0.001) were also independently associated with disease-free survival (DFS). Pathological T stage (HR p<0.001, 95% CI 1.537-3.021, p<0.001), pathological N stage (HR1.571, 95% CI 1.157-2.258, p<0.001), and preoperative NLR (HR 1.509, 95% CI 1.153-3.104, p=0.001) were independent risk factors for disease-specific survival (DSS).

conclusionThe preoperative NLR is considered to be a useful predictor of postoperative survival in SSCC patients.

Indexed as

albumin-to-globulin ratiopatientsrisk factorsinonasal carcinomasurvival

Identifiers

PMID31814768
PMCPMC6863176

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