Evidence map›Paper›PMID 31814459›Full record

ArticleInhalation toxicology

Autoimmune markers for progression of Libby amphibole lamellar pleural thickening.

Jean C Pfau, Tracy McNew, Kerensa Hanley, Lindsay Swan, Brad Black

Open access · greenAbstract read
In one paragraph

Article in Inhalation toxicology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Autoantibodies and cancer among asbestos-exposed cohorts in Western Australia.Journal of toxicology and environmental health. Part A · 2021
    Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jean C PfauDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.ORCID 0000-0002-1249-7195
Tracy McNewCenter for Asbestos Related Diseases, Libby, MT, USA.
Kerensa HanleyCenter for Asbestos Related Diseases, Libby, MT, USA.
Lindsay SwanDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.
Brad BlackCenter for Asbestos Related Diseases, Libby, MT, USA.
Center for Asbestos Related Disease · USMontana State University · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
NCATS NIH HHS UL1 TR002319
6 · The paper itself

Abstract

Exposure to Libby Asbestiform Amphibole (LAA) is associated with asbestos-related diseases, including mesothelioma, pulmonary carcinoma, pleural fibrosis, and systemic autoimmune diseases. The pleural fibrosis can manifest as a rapidly progressing lamellar pleural thickening (LPT), which causes thoracic pain, dyspnea, and worsening pulmonary function tests (PFT). It is refractory to treatment and frequently fatal.

Indexed as

Antibodies, AntinuclearAsbestos, AmphiboleAutoantibodiesBiomarkersCell LineCollagenCytokinesGene Expression RegulationHumansPleuraSensitivity and SpecificityAntibodies, AntinuclearAsbestos, AmphiboleAutoantibodiesBiomarkersCollagenCytokinesasbestosautoantibodiescytokinesPleural diseaseROCsensitivityspecificity

Identifiers

PMID31814459
PMCPMC7450909
OpenAlexW2994595052

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.