Evidence map›Paper›PMID 31814164›Full record

Trial reportAmerican journal of hematology2020

Cerebral hemodynamics and metabolism are similar in sickle cell disease patients with hemoglobin SS and Sβ

Ifeanyi Ikwuanusi, Lori C Jordan, Chelsea A Lee, Niral J Patel, Spencer Waddle, Sumit Pruthi, L Taylor Davis, Allison Griffin, Michael R DeBaun, Adetola A Kassim and 1 more

Open access · bronzeAbstract readClinical TrialLetter
In one paragraph

Trial report in American journal of hematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Choroid plexus perfusion in sickle cell disease and moyamoya vasculopathy: Implications for glymphatic flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ifeanyi IkwuanusiDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Lori C JordanDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0001-7240-0415
Chelsea A LeeDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Niral J PatelDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Spencer WaddleDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Sumit PruthiDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
L Taylor DavisDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Allison GriffinDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Michael R DeBaunDepartment of Pediatrics, Vanderbilt-Meharry Center for Excellence in Sickle Cell Disease, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-0574-1604
Adetola A KassimDepartment of Internal Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, Tennessee.
Manus J DonahueDepartment of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-4123-9275
Vanderbilt University Medical Center · US

Funding

Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Imaging collaterals and tissue metabolism in patients with Moyamoya syndromeR01NS097763 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DONAHUE, MANUS J · 2016 to 2020
$1.7M
MRI-based quantitative brain oxygen metabolism identifying high risk of infarct recurrence in sickle cell anemiaR01NS096127 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JORDAN, LORI CHAFFIN · 2016 to 2020
$1.7M
Mentoring in Patient-Oriented Research focused on Neurological Complications of Sickle Cell DiseaseK24HL147017 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI JORDAN, LORI CHAFFIN · 2019 to 2023
$547k
American Heart Association-American Stroke Association 14CSA20380466-JORDANNHLBI NIH HHS K24 HL147017NICHD NIH HHS U54 HD083211NIH HHS 5R01NS097763NINDS NIH HHS R01 NS096127NINDS NIH HHS R01 NS097763
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle CellCerebrovascular CirculationHemodynamicsHemoglobin, SickleThalassemiaAdolescentAdultChildFemaleHumansMaleHemoglobin, Sickle

Identifiers

PMID31814164
PMCPMC7017969
OpenAlexW2994205830

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.