Evidence map›Paper›PMID 31813347›Full record

ArticleHypertension (Dallas, Tex. : 1979)2020

Sex Differences in the Sympathetic Neural Recruitment and Hemodynamic Response to Head-Up Tilt in Older Hypertensives.

Mark B Badrov, Yoshiyuki Okada, Jeung-Ki Yoo, Wanpen Vongpatanasin, J Kevin Shoemaker, Benjamin D Levine, Qi Fu

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Human sympathetic neuronal discharge and recruitment patterns regulate neuropeptide Y bioavailability.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  6. Greater resting muscle sympathetic nerve activity reduces cold pressor autonomic reactivity in older women, but not older men.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  7. Article
  8. Sex differences in the effect of acute intermittent hypoxia on respiratory modulation of sympathetic activity.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Article
  9. Review
  10. Sympathetic neural recruitment strategies following acute intermittent hypoxia in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mark B BadrovFrom the Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas (M.B.B., Y.O., J.-K.Y., B.D.L., Q.F.).
Yoshiyuki OkadaFrom the Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas (M.B.B., Y.O., J.-K.Y., B.D.L., Q.F.).
Jeung-Ki YooFrom the Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas (M.B.B., Y.O., J.-K.Y., B.D.L., Q.F.).
Wanpen VongpatanasinUniversity of Texas Southwestern Medical Center, Dallas (M.B.B., Y.O., J.-K.Y., W.V., B.D.L., Q.F.).
J Kevin ShoemakerSchool of Kinesiology (J.K.S.), Western University, London, Ontario, Canada.
Benjamin D LevineFrom the Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas (M.B.B., Y.O., J.-K.Y., B.D.L., Q.F.).
Qi FuFrom the Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas (M.B.B., Y.O., J.-K.Y., B.D.L., Q.F.).
The University of Texas Southwestern Medical Center · USPresbyterian Hospital · USInstitute for Exercise and Environmental Medicine · US

Funding

Hypertension and Antihypertensive Therapy in Elderly WomenR01HL091078 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI FU, QI · 2008 to 2011
$1.6M
NHLBI NIH HHS R01 HL091078
6 · The paper itself

Abstract

This study tested the hypothesis that older hypertensive women display augmented pressor responses and aberrant sympathetic neural discharge patterning in response to orthostatic stress versus older hypertensive men. We evaluated, in older hypertensive and normotensive men and women (n=12 each group), blood pressure, heart rate, cardiac index (acetylene rebreathing), total peripheral resistance, and muscle sympathetic nerve activity (microneurography) at baseline (supine; 3 minutes) and during graded head-up tilt (30° for 5 minutes and 60° for 20 minutes). Sympathetic action potential discharge patterns were studied using wavelet-based methodology. In the upright posture, systolic and diastolic blood pressure responses were greater in hypertensive women versus hypertensive men and normotensive women (

Indexed as

AgedBaroreflexBlood PressureFemaleHeart RateHumansHypertensionMalePostureSex FactorsSympathetic Nervous SystemTilt-Table Testagingblood pressurehypertensionmuscle sympathetic nerve activitysympathetic nervous systemvasoconstriction

Identifiers

PMID31813347
PMCPMC7004478
OpenAlexW2992792289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.