Evidence map›Paper›PMID 31813116›Full record

ArticleProgress in biomaterials2019

Synthesis of plate-like β-tricalcium phosphate nanoparticles and their efficiency in remineralization of incipient enamel caries.

Roghayyeh Marefat Seyedlar, Mohammadbagher Rezvani, Samira Barari, Mohammad Imani, Azizollah Nodehi, Mohammad Atai

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Progress in biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06561789 (Efficacy of Remineralizing Potential of β-Tricalcium Phosphate Nanoparticles Versus Functionalizedβ-Tricalcium Phosphate Nanoparticles), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06561789 nacompletednot on this mapstarted 2023, after this paper: background citation

Efficacy of Remineralizing Potential of β-Tricalcium Phosphate Nanoparticles Versus Functionalizedβ-Tricalcium Phosphate Nanoparticles

TypeinterventionalSponsorAya Magdy ElsadanyRan2023 to 2023Enrolled60ConditionsWhite Spot Lesions[Initial Caries]on Smooth Surface of ToothArmsFunctionalized Nano ᵦ tricalcium phosphate particles, Nano ᵦ tricalcium phosphate particles, sodium fluoride mouth wash
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. In vitro comparative evaluation of physical and chemical properties of surface enamel after using APF and SDF with or without laser activation.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Roghayyeh Marefat SeyedlarIran Polymer and Petrochemical Institute (IPPI), Pajouhesh Blvd., Karaj Highway, P.O. Box 14965-115, Tehran, 1497713115, Iran.
Mohammadbagher RezvaniSurgery Department, Shahed University, Faculty of Dentistry, Tehran, Iran.
Samira BarariSurgery Department, Shahed University, Faculty of Dentistry, Tehran, Iran.
Mohammad ImaniIran Polymer and Petrochemical Institute (IPPI), Pajouhesh Blvd., Karaj Highway, P.O. Box 14965-115, Tehran, 1497713115, Iran.
Azizollah NodehiIran Polymer and Petrochemical Institute (IPPI), Pajouhesh Blvd., Karaj Highway, P.O. Box 14965-115, Tehran, 1497713115, Iran.
Mohammad AtaiIran Polymer and Petrochemical Institute (IPPI), Pajouhesh Blvd., Karaj Highway, P.O. Box 14965-115, Tehran, 1497713115, Iran. m.atai@ippi.ac.ir.ORCID http://orcid.org/0000-0002-9764-6734
Iran Polymer and Petrochemical Institute · IRShahed University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to synthesize nano-sized β-tricalcium phosphate (nano-TCP) particles and determine its concentration-dependent properties on incipient enamel caries lesions. Nano-TCP was synthesized as a wet chemical through a method using low concentration of precursors and low addition rate of calcium nitrate tetrahydrate as a second phase. Morphology and phase composition of the particles were analyzed by SEM, XRD, and EDXA techniques. Incipient enamel lesions were created in human premolars with an acidic buffer. The teeth were then incubated in aqueous dispersions of nano-TCP as remineralization solutions. Sodium fluoride solution and deionized water were used as positive and negative control groups, respectively. The quality and thickness of the remineralized layer on enamel were investigated using SEM. The data were statistically analyzed by analysis of variance (ANOVA) and post hoc Tukey's test. The synthesized nano-TCP mostly consisted of porous platelet-like crystals of 50-100 nm thickness and pore diameters of 100-300 nm. SEM observation showed that a homogenous layer was formed on the surface of the enamels remineralized in nano-TCP solutions. The thickness of the mineralized layer was dependent on the incubation time and nano-TCP concentration.

Indexed as

Incipient enamel caries lesionsNanoparticlePlatelet morphologyRemineralizationβ-Tricalcium phosphate

Identifiers

PMID31813116
PMCPMC6930320
OpenAlexW2994523535

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.