ArticlePlant molecular biology2020
The Arabidopsis kinase-associated protein phosphatase KAPP, interacting with protein kinases SnRK2.2/2.3/2.6, negatively regulates abscisic acid signaling.
Article in Plant molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Dry side of the core: a meta-analysis addressing the original nature of the ABA signalosome at the onset of seed imbibition.Frontiers in plant science · 2023Pooled it
- A phosphatidic acid-based retrograde signaling pathway responsive to abiotic stress in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- The HAESA family of receptor-like kinases: abscission pathways and emerging functions.Frontiers in plant science · 2026Review
- Genome-Wide Identification ofPlants (Basel, Switzerland) · 2025Article
- Overexpression of a 'Plants (Basel, Switzerland) · 2024Article
- StSN2 interacts with the brassinosteroid signaling suppressor StBIN2 to maintain tuber dormancy.Horticulture research · 2023Article
- The role of forkhead-associated (FHA)-domain proteins in plant biology.Plant molecular biology · 2023Review
- Height to first pod: A review of genetic and breeding approaches to improve combine harvesting in legume crops.Frontiers in plant science · 2022Review
- A Genome Wide Association Study Revealed Key Single Nucleotide Polymorphisms/Genes Associated With Seed Germination inFrontiers in plant science · 2022Article
- The Multifaceted Regulation of SnRK2 Kinases.Cells · 2021Review
- Reduced expression of a subunit gene of sucrose non-fermenting 1 related kinase, PpSnRK1βγ, confers flat fruit abortion in peach by regulating sugar and starch metabolism.BMC plant biology · 2021Article
- Signaling mechanisms in abscisic acid-mediated stomatal closure.The Plant journal : for cell and molecular biology · 2021Review
- Role of Raf-like kinases in SnRK2 activation and osmotic stress response in plants.Nature communications · 2020Review
- AtSnRK2.4 Functions as an ABA-Responsive Protein Kinase in Arabidopsis.Physiologia plantarumArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
key messageThe kinase-associated protein phosphatase, KAPP, is negatively involved in abscisic acid (ABA) signaling. KAPP interacts physically with SnRK2.2, SnRK2.3 and SnRK2.6, and functionally acts upstream of SnRK2.2 and SnRK2.3. The kinase-associated protein phosphatase (KAPP) has been reported to be involved in the regulation of many developmental and signaling events, but it remains unknown whether KAPP is involved in ABA signaling. Here, we report that KAPP is negatively involved in ABA-mediated seed germination and early seedling growth in Arabidopsis thaliana. The two loss-of-function mutants of KAPP, kapp-1 and kapp-2, exhibit increased ABA sensitivity in ABA-induced seed germination inhibition and post-germination growth arrest. The three closely-related protein kinase, (SNF1)-related protein kinase SnRK2.2, SnRK2.3 and SnRK2.6, which play critical roles in ABA signaling, interact and co-localize with KAPP. Genetic evidence showed that the ABA-hypersensitive phenotypes caused by KAPP mutation were suppressed by the double mutation of SnRK2.2 and SnRK2.3, indicating that KAPP functions upstream of SnRK2.2 and SnRK2.3 in ABA signaling. RNA-sequencing analysis revealed that KAPP mutation affects expression of multiple ABA-responsive genes. These results demonstrated that KAPP is negatively involved in plant response to ABA, which help to understand the complicated ABA signaling mechanism.
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