ArticleInternational ophthalmology2020
Relationship between OSDI questionnaire and ocular surface changes in glaucomatous patients.
Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Effect of first-line topical medications for the treatment of glaucoma on the ocular surface in a Latin American population.International ophthalmology · 2026Observational
- Polypharmacy in glaucoma management: a narrative review.Irish journal of medical science · 2026Review
- Ocular Surface Changes and Glaucoma: A Prospective Contralateral Study of IOP-Reducing Eyedrops versus iStent Inject Surgery.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Evaluation of the effect of intravitreal injections on corneal epithelial, scleral and limbal region changes in diabetic retinopathy by AS-OCT.International ophthalmology · 2024Article
- Management of Glaucoma-Related Dry Eye Disease with Intense Pulsed Light: A Randomized Control Study.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- High-intensity interval training in patients with glaucoma (HIT-GLAUCOMA): protocol for a multicenter randomized controlled exercise trial.Frontiers in physiology · 2024Article
- Comparison of Transcriptomic Analysis of the Conjunctiva in Glaucoma-Treated Eyes with Dry Eyes and Healthy Controls.Biomolecules · 2023Article
- Characteristics of tear meniscus using a spectral domain optical coherence tomography in medically controlled glaucoma.Indian journal of ophthalmology · 2023Observational
- Relationship between the number of glaucoma medications, ocular surface disorder, and treatment adherence.Arquivos brasileiros de oftalmologia · 2023Article
- Matching-adjusted indirect comparison of phase 3 clinical trial outcomes: OC-01 (varenicline solution) nasal spray and cyclosporine a 0.05% ophthalmic emulsion for the treatment of dry eye disease.Journal of managed care & specialty pharmacy · 2022Review
- Correlation of meiboscale symptom score and sign score for primary meibomian gland dysfunction in Indian eyes - A cross-sectional study.Indian journal of ophthalmology · 2022Article
- Common ocular findings in patients with acne rosacea.International ophthalmology · 2022Article
- Intense pulsed light-based treatment for the improvement of symptoms in glaucoma patients treated with hypotensive eye drops.Eye and vision (London, England) · 2022Article
- Efficacy, Safety and Patient-Reported Outcomes with Preservative-Free (PF) Tafluprost or PF-Dorzolamide/Timolol Compared with Preserved Latanoprost: A Prospective Multicenter Study in Korean Glaucoma Patients with Ocular Surface Disease.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Dry eye disease and tear film assessment through a novel non-invasive ocular surface analyzer: The OSA protocol.Frontiers in medicine · 2022Article
- Effects of Glaucoma Medication on Dry Eye Syndrome and Quality of Life in Patients with Glaucoma.Korean journal of ophthalmology : KJO · 2021Article
- Validation of the Arabic version of the Ocular Surface Disease Index Questionnaire.International journal of ophthalmology · 2021Article
- Ocular Surface Evaluation after Switch from Latanoprost 0.005% to Latanoprostene Bunod 0.024.Journal of current glaucoma practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo evaluate the quality of life of glaucoma patients using the Ocular Surface Disease Index (OSDI) questionnaire and their association with dry eye clinical signs.
methodsThe study included patients into three groups. The treated group diagnosed with bilateral open-angle glaucoma and treated with one or more topical medication at least 1 year. The operated group underwent glaucoma surgery without the need for topical medications. The control group entered subjects without ocular diseases or previous surgeries. Dry eye clinical signs were evaluated; noninvasive tear break-up time, Meibomian gland depletion (MGD), and conjunctival hyperemia were measured using the Keratograph 5 M. The total-OSDI (T-OSDI) score was divided into the visual field-OSDI and discomfort-OSDI scores.
resultsTwo hundred and nine subjects participated in this cross-sectional study, 147 using glaucoma medications, 21 patients underwent glaucoma surgery and 41 were controls. The T-OSDI and subscores were higher in glaucoma patients compared with controls (p < 0.05); we found no differences between treated and surgically groups. Correlations were observed between the T-OSDI values and Schirmer test (p = 0.016), ocular surface staining (p < 0.001) and the MGD (p = 0.006). The subscores were associated with the ocular surface staining (VF p = 0.013 and D p = 0.003). In treated patients, the number of drops per day correlates with T-OSDI and subscores (p = 0.017 and p = 0.005).
conclusionOSDI scores increased in the glaucoma patients compared to controls without significant changes between treated and surgical patients. OSDI scores were associated to dry eye signs and medication in glaucoma patients.
Indexed as
Identifiers
31813109What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.