ArticleJournal of echocardiography2020
Significance of left atrial overload by electrocardiogram in the assessment of left ventricular diastolic dysfunction.
Article in Journal of echocardiography, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Electrocardiographic Features of Left Ventricular Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction: A Systematic Review.Frontiers in cardiovascular medicine · 2021Pooled it
- P-Wave Indices and the Risks of Incident Atrial Fibrillation and Ischemic Stroke in Black Adults: The Jackson Heart Study.Journal of the American Heart Association · 2025Article
- Identifying heart failure dynamics using multi-point electrocardiograms and deep learning.European heart journal. Digital health · 2025Article
- Comparison of Electrocardiographic Parameters by Gender in Heart Failure Patients with Preserved Ejection Fraction via Artificial Intelligence.Diagnostics (Basel, Switzerland) · 2023Article
- Prognostic Value of PtfV1 in Long-Term Outcomes of Patients with Unstable Angina.International journal of general medicine · 2023Article
- Early changes in myocyte contractility and cardiac function in streptozotocin-induced type 1 diabetes in rats.PloS one · 2020Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough assessment of left ventricular (LV) diastolic function (DF) using echocardiography is important, it is not always feasible in the clinical practice. On the other hand, left atrial (LA) overload shown by electrocardiogram (ECG) indicates LA pressure rise and LA dilatation. The purpose of this study is to examine whether LA overload by ECG can be used as an aid for evaluation of LVDF.
methodsThere were 117 subjects who underwent echocardiography and ECG on the same day. The duration of P-wave (P-duration) in lead II, the amplitude and duration of P-wave negative phase in lead V1 were measured by ECG, and terminal force (PTFV1) was calculated. We analyzed the relationships between LVDF grades and LA overload signs.
resultsP-duration showed a good correlation with LA volume index (LAVi) (r = 0.673, P < 0.0001) and PTFV1 showed reasonable correlations with both LAVi and average E/e' (both, r = 0.575, P < 0.0001). Both P-duration and PTFV1 showed significant differences among the LVDF classes (P < 0.0001). Among the ECG indices, P-duration [Formula: see text] 110 ms was the most powerful to judge the presence of LV diastolic dysfunction with 86% of sensitivity and specificity.
conclusionsP-duration ≥ 110 ms is useful to suggest the presence of LV diastolic dysfunction. Conventional ECG criteria (P-duration ≥ 120 ms and PTFV1 [Formula: see text] 0.04 mm·s) are highly specific and suggest the presence of LV diastolic dysfunction with LA pressure rise. Echocardiography and ECG should be used in a complementary way when LVDF grades are indeterminate.
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