Evidence map›Paper›PMID 31813045›Full record

Trial reportEuropean journal of applied physiology2020

Ischemic preconditioning has no effect on maximal arm cycling exercise in women.

Gustavo R Mota, Zachary B Rightmire, Jeffrey S Martin, James R McDonald, Andreas N Kavazis, David D Pascoe, L Bruce Gladden

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07497659 (Ischemic Preconditioning and Cardiac Demand During Resistance Exercise in Older Women), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07497659 nacompletednot on this mapstarted 2025, after this paper: background citation

Ischemic Preconditioning and Cardiac Demand During Resistance Exercise in Older Women: A Randomized Clinical Trial

TypeinterventionalSponsorUniversidade Federal do Triangulo MineiroRan2025 to 2025Enrolled30ConditionsBlood Pressure, Hemodynamic Response, Rating of Perceived Exertion, Heart RateArmsIschemic Preconditioning, Sham Preconditioning
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gustavo R MotaHuman Performance and Sport Research Group, Department of Sport Sciences, Institute of Health Sciences, Federal University of Triangulo Mineiro, Av. Tutunas, 490, Uberaba, MG, 38061-500, Brazil. grmotta@gmail.com.ORCID http://orcid.org/0000-0002-6109-0658
Zachary B RightmireSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Jeffrey S MartinSchool of Kinesiology, Auburn University, Auburn, AL, USA.ORCID http://orcid.org/0000-0001-6762-086X
James R McDonaldSchool of Kinesiology, Auburn University, Auburn, AL, USA.
Andreas N KavazisSchool of Kinesiology, Auburn University, Auburn, AL, USA.
David D PascoeSchool of Kinesiology, Auburn University, Auburn, AL, USA.
L Bruce GladdenSchool of Kinesiology, Auburn University, Auburn, AL, USA.ORCID http://orcid.org/0000-0001-5193-7440

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigated the effect of ischemic preconditioning (IPC) on performance of a 3 min maximal effort arm ergometer test in young women.

methodsTwenty healthy women (23.1 (SD 3.3) years) performed a 3 min maximal effort arm cycling exercise, preceded by IPC on both arms or SHAM in a counterbalanced randomized crossover design. Both blood flow (via high resolution ultrasound; n = 17) and muscle oxygenation/deoxygenation (via near infrared spectroscopy; n = 5) were measured throughout the IPC/SHAM. Performance and perceptual/physiological (i.e., heart rate, blood lactate, rating of perceived exertion, and triceps brachialis oxygenation) parameters were recorded during the exercise test.

resultsOcclusion during IPC completely blocked brachial artery blood flow, decreased oxygenated hemoglobin/myoglobin (Δ[oxy(Hb + Mb)]), and increased deoxygenated Hb/Mb (Δ[deoxy(Hb + Mb)]). There were no differences (P > 0.797) in performance (peak, mean, and end power output) or in any perceptual/physiological variables during the 3 min all-out test between IPC/SHAM. During exercise, Δ[oxy(Hb + Mb)] initially decreased with no differences (P ≥ 0.296) between conditions and returned towards baseline by the completion of the test while Δ[deoxy(Hb + Mb)] increased with no differences between conditions and remained elevated until completion of the test (P ≥ 0.755).

conclusionsWe verified the successful application of IPC via blood flow and NIRS measures but found no effects on performance of a 3 min maximal effort arm cranking test in young women.

Indexed as

ArmIschemic PreconditioningAdultExerciseExercise TestFemaleHumansMuscle, SkeletalOxygen ConsumptionYoung AdultBlood flow restrictionErgogenic aidFemalesUpper limbs

Identifiers

PMID31813045

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.