ArticlePediatric nephrology (Berlin, Germany)2020
Correlation of urine protein/creatinine ratios to 24-h urinary protein for quantitating proteinuria in children.
Article in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Proteinuria in adolescence.Pediatric nephrology (Berlin, Germany) · 2026Review
- Can urinary albumin-creatinine ratio be used as a surrogate for protein-creatinine ratio in the diagnosis and management of pediatric steroid sensitive nephrotic syndrome?Pediatric nephrology (Berlin, Germany) · 2026Article
- Congenital Hepatic Fibrosis and/or Autosomal Recessive Polycystic Kidney Disease: A Single-center Experience.Pediatric gastroenterology, hepatology & nutrition · 2026Article
- Paediatric multicystic dysplastic kidney disease in Cape Town, South Africa.BMC nephrology · 2025Article
- Investigation of Microvascular Involvement Through Nailfold Capillaroscopic Examination in Children with Familial Mediterranean Fever.Medicina (Kaunas, Lithuania) · 2025Article
- Validation and optimization of classification criteria for childhood-onset systemic lupus erythematosus in a multi-center Chinese cohort.Frontiers in immunology · 2025Article
- Explore the Value of Multi-Parameter MRI in Non-Invasive Assessment of Prognostic Risk and Oxford Classification in Children with IgAN or IgAVN.Bioengineering (Basel, Switzerland) · 2024Article
- Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- How to define and assess the clinically significant causes of hematuria in childhood.Pediatric nephrology (Berlin, Germany) · 2023Article
- Etiology, Comorbidities, and Rate of Progression of Pediatric Chronic Kidney Disease: A Cohort Study.Indian journal of pediatrics · 2023Article
- Etiology and outcomes of acute kidney disease in children: a cohort study.Clinical and experimental nephrology · 2023Article
- Comparison of three spot proteinuria measurements for pediatric nephrotic syndrome: based on the International pediatric Nephrology Association 2022 Guidelines.Renal failure · 2023Article
- Estimation of 24 h Urine Protein Versus Spot Urine Protein Creatinine Ratio in Patients with Kidney Disease.Indian journal of clinical biochemistry : IJCB · 2022Article
- Diagnostic efficacy and influence factors of urinary protein/creatinine ratio replacing 24-h urine protein as an evaluator of proteinuria in children.International urology and nephrology · 2022Article
- Serum IL-6 as a marker of disease progression in interstitial nephritis.American journal of translational research · 2022Article
- Clinical Efficacy of Persian Medicine Diet Combined with Western Medicine-Based Diet on Proteinuria in Pediatric Nephrotic Syndrome: A Randomized Controlled Clinical Trial.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Reference values of urine protein/creatinine ratio in healthy Dalian adults.Journal of clinical laboratory analysis · 2021Article
- Children with Intestinal Failure Maintain Their Renal Function on Long-Term Parenteral Nutrition.Nutrients · 2021Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to evaluate the correlation and consistency between urine protein/creatinine ratio (UPCR) and 24-h urine protein (24HUPr) in children, and to determine cutoff values of UPCR relative to 24HUPr at 100 mg/m
methodsThree hundred sixty-six children were enrolled, including 81 controls, 109 with Henoch-Schönlein purpura nephritis, 167 with nephrotic syndrome, 5 with IgA nephropathy, and 4 with lupus nephritis. Patients were divided into three groups: normal group; non-nephrotic-range proteinuria group; nephrotic-range proteinuria group. The cutoff values of UPCR in predicting the different levels of proteinuria were determined using ROC curve analysis.
resultsUPCR was positively correlated with 24HUPr (r = 0.915, p < 0.01). Bland-Altman diagrams showed that UPCR and 24HUPr had good consistency, and > 95% spots of UPCR and 24HUPr were within 95% confidence intervals. Relative to 24HUPr at 100 mg/m
conclusionsUPCR showed strong correlation and consistency with 24HUPr for evaluating levels of proteinuria in children. UPCR < 0.2 g/g Cr can be considered a criterion for normal-range proteinuria. Instead of 24HUPr ≥ 1000 mg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.