Evidence map›Paper›PMID 31812951›Full record

ArticleAging2019

LncRNA EPIC1 downregulation mediates hydrogen peroxide-induced neuronal cell injury.

Jian Sun, Jinyu Zheng, Ya Li, Ming Yan, Ping Li, Lili Ma

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Jian SunDepartment of Anesthesiology, Huai'an Maternity and Child Healthcare Hospital, Yangzhou University Medical School, Huai'an, China.
Jinyu ZhengDepartment of Neurosurgery, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, China.
Ya LiThe Central Lab, North District, Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou, China.
Ming YanDepartment of Anesthesiology, Huai'an Maternity and Child Healthcare Hospital, Yangzhou University Medical School, Huai'an, China.
Ping LiDepartment of Radiotherapy and Oncology, Affiliated Kunshan Hospital to Jiangsu University, Kunshan, China.
Lili MaDepartment of Anesthesiology, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and The Affiliated Cancer of Hospital Nanjing Medical University, Nanjing, China.
Yangzhou University · CNFirst People's Hospital of Kunshan · CNNanjing Medical University · CNSecond People’s Hospital of Huai’an · CNSuzhou Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive oxidative stress causes neuronal cell injury. Long non-coding RNA (LncRNA) EPIC1 (Lnc-EPIC1) is a MYC-interacting LncRNA. Its expression and potential functions in hydrogen peroxide (H

Indexed as

Cells, CulturedCell SurvivalDown-RegulationGene Expression RegulationGene Knockdown TechniquesHumansHydrogen PeroxideNeuronsRNA, Long NoncodingHydrogen PeroxideRNA, Long Noncodinghydrogen peroxidelncRNA EPIC1MYCneuronal cells

Identifiers

PMID31812951
PMCPMC6932932
OpenAlexW2995953897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.