ArticleInternational journal of pediatric otorhinolaryngology2020
Current evaluation and management of plastic bronchitis in the pediatric population.
Article in International journal of pediatric otorhinolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 49 citations in OpenAlex.
- Case Series: clinical challenges in pediatric plastic bronchitis.Frontiers in pediatrics · 2026Article
- A literature review: progress in the study of plastic bronchitis.Frontiers in pediatrics · 2026Review
- A nomogram prediction model for plastic bronchitis in children with refractoryFrontiers in pediatrics · 2026Article
- PLR/SII/D-dimer iron triangle: a novel precision prediction strategy forFrontiers in medicine · 2026Article
- Development and validation of a nomogram for predicting recurrent plastic bronchitis in children with Mycoplasma pneumoniae pneumonia.Frontiers in pediatrics · 2026Article
- Clinical characteristics and risk factor analysis of children with severeTranslational pediatrics · 2025Article
- Clinical characteristics and predictor analysis of pediatric Mycoplasma pneumoniae pneumonia with small segment molded sputum plugs: a retrospective study.Italian journal of pediatrics · 2025Article
- Interventions for Fontan Pathway Obstruction in Patients Following Total Cavopulmonary Connection.Journal of clinical medicine · 2025Article
- Bronchoalveolar lavage cytokine profile and clinical features as risk predictors of plastic bronchitis in children with Mycoplasma pneumoniae pneumonia.Italian journal of pediatrics · 2025Article
- Risk analysis of poor prognosis and follow-up observation of children withFrontiers in pediatrics · 2025Article
- Risk factor analysis of plastic bronchitis among 126 children with macrolide-resistantFrontiers in pediatrics · 2025Article
- Nebulized alteplase in coronavirus disease 2019 pneumonia: a case series.Journal of medical case reports · 2024Article
- Establishment of a Mouse Model ofMicroorganisms · 2024Article
- Analysis of the Risk Factors for Plastic Bronchitis in Children with Severe Adenovirus Pneumonia: A Retrospective Study.Infection and drug resistance · 2024Article
- Plastic bronchitis secondary to thoracotomy in an adult: A case report.Respiratory medicine case reports · 2024Article
- Clinical features and risk factors of plastic bronchitis caused by Mycoplasma pneumoniae pneumonia in children.BMC pulmonary medicine · 2023Article
- Eosinophilic plastic bronchitis: Case series and review of the literature.Pediatric pulmonology · 2023Review
- Clinical and Radiological Evaluation and Follow-Up of Patients with Noncardiac Plastic Bronchitis.Turkish archives of pediatrics · 2023Article
- [Clinical characteristics of plastic bronchitis and risk factors for recurrence in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Outcomes and Risk Factor Analysis of Plastic Bronchitis Among 321 Children with Influenza Pneumonia After Bronchoscopy Examination.Infection and drug resistance · 2023Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo describe a multidisciplinary approach for the treatment of plastic bronchitis (PB) in children.
methodsRetrospective chart review of children with PB between 1997 and 2017. Data regarding clinical presentation, diagnosis, management, and outcomes were analyzed.
resultsOf 34 patients presenting with PB, 24 had single ventricle (SV) heart disease, 9 had pulmonary disease, and one had no underlying disease. Median (IQR: interquartile range) age at the time of PB diagnosis was 5.5 years (IQR: 9.0). Presenting symptoms included cough productive of casts (n = 27, 79%), wheezing (n = 5, 15%), dyspnea (n = 18, 53%), hypoxia (n = 31, 91%), and respiratory failure (n = 9, 26%). Diagnosis was made based on clinical evaluation, bronchoscopy findings, and/or pathology of casts. Treatment methods included bronchoscopy for cast removal (25% of SV patients, 91% of non-SV patients), chest physiotherapy (SV: 92%, non-SV: 45%), albuterol (SV: 79%, non-SV: 73%), inhaled steroids (SV: 75%, non-SV: 18%), nebulized hypertonic saline (SV: 29%, non-SV: 9%), nebulized heparin (SV: 8%, non-SV: 55%), nebulized tissue plasminogen activator (tPA; SV: 33%, non-SV: 9%), inhaled Dornase Alfa (SV: 54%, non-SV: 9%), antibiotics (SV: 46%, non-SV: 45%), systemic steroids (SV: 13%, non-SV: 45%), and lymphatic embolization (SV: 8%, non-SV: 45%). Of SV patients, 11 had no recurrence, 5 underwent heart transplantation, one awaits transplant, and 3 died due to cardiac disease. Three patients with respiratory disease had recurrent PB and one died from MRSA pneumonia.
conclusionPB is a highly morbid disease with limited treatment options. Bronchoscopy and chest physiotherapy for airway clearance are among the most-utilized therapies.
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