ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2020
Outcomes From Right Versus Left Deceased-Donor Kidney Transplants: A US National Cohort Study.
Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of Vascular Anastomosis Time on Kidney Transplant Outcomes - A Systematic Review.Transplant international : official journal of the European Society for Organ Transplantation · 2026Pooled it
- Expanding boundaries: The evolution and future of living donor kidney transplantation.World journal of transplantation · 2025Article
- Living donor transplant: RightWorld journal of transplantation · 2025Article
- Postkidney Transplant Delayed Graft Function Outcomes Are Not Worsened by Deceased Donor Type.Clinical transplantation · 2025Article
- Significantly reduced patient and graft survival for left vs right donor lungs for lung transplant recipients.JHLT open · 2024Article
- A Novel Cooling Device for Kidney Transplant Surgery.Surgical innovation · 2024Article
- Transplanting a left or right donor kidney into the left or right iliac fossa: importance of laterality and site of venous anastomosis.Updates in surgery · 2023Article
- Management and Outcome After Early Renal Transplant Vein Thrombosis: A French Multicentre Observational Study of Real-Life Practice Over 24 Years.Transplant international : official journal of the European Society for Organ Transplantation · 2023Observational
- Transplant and Recipient Factors in Prediction of Kidney Transplant Outcomes: A UK-Wide Paired Analysis.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
RATIONALE &
objectiveThere may be important transplant-related differences between right and left kidneys, including logistical/surgical considerations about vessel length for the right compared to the left kidney from the same donor. Because US centers choose between the right and left kidney when their recipient is ranked higher on a "match-run," we sought to determine whether deceased-donor right kidneys have had worse posttransplantation outcomes than left kidneys. STUDY
designPaired Organ Procurement and Transplantation Network analysis. SETTING &
participantsDeceased-donor kidney pairs transplanted during 1990 to 2016. EXPOSURE: Right versus left kidney controlling for other significant factors. OUTCOMES: Delayed graft function (DGF), all-cause and death-censored graft failure, and mortality. ANALYTICAL APPROACH: Multivariable conditional logistic regression for DGF; proportional hazards models (conditional on same donor) for failure/mortality with right kidneys (operationalized as 6-month time-varying coefficients) adjusting for DGF and other confounders.
results87,112 recipient pairs shared the following donor characteristics: mean age of 41 ± 14 years, 60% males, and 11% with cardiac death. Recipient characteristics were numerically similar by donor kidney side but with some statistical differences given the sample size. Right kidneys had slightly longer cold ischemia time. DGF occurred more often for right kidneys (28% vs 25.8%; P < 0.001; adjusted OR, 1.15 [95% CI, 1.12-1.17]). The adjusted hazard ratio (aHR) for all-cause graft failure with right kidneys within 6 months was 1.07 (95% CI, 1.03-1.11), and was 0.99 (95% CI, 0.97-1.01) thereafter. The aHRs for death-censored graft failure with right kidneys before and after 6 months were 1.11 (95% CI, 1.06-1.16) and 0.96 (95% CI, 0.93-0.99), respectively; the corresonding aHRs for mortality were 0.99 (95% CI, 0.93-1.04) and 1.00 (95% CI, 0.98-1.03), respectively. LIMITATIONS: Registry data, different transplant eras, reasons for kidney side unavailable.
conclusionsThere is modest association for transplantation of right kidneys with DGF and graft loss within the first 6 months, which is lost beyond this time point. These findings do not support the use of laterality of deceased-donor kidneys as an important factor in organ acceptance decisions.
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