Evidence map›Paper›PMID 31812224›Full record

ArticleThe American journal of cardiology2020

Improving Care Pathways for Acute Coronary Syndrome: Patients Undergoing Percutaneous Coronary Intervention.

Amit P Amin, John A Spertus, Hemant Kulkarni, Christian McNeely, Sunil V Rao, Duane Pinto, John A House, John C Messenger, Richard G Bach, Abhinav Goyal and 7 more

Abstract readMulticenter Study
In one paragraph

Article in The American journal of cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Amit P AminCardiovascular Division, Washington University School of Medicine, St. Louis, Missouri; Barnes-Jewish Hospital, St. Louis, Missouri; Center for Value and Innovation, Washington University School of Medicine, St. Louis, Missouri. Electronic address: aamin@wustl.edu.
John A SpertusBarnes-Jewish Hospital, St. Louis, Missouri; Saint Luke's Mid America Heart Institute and the University of Missouri - Kansas City, Kansas City, Missouri.
Hemant KulkarniM and H Research, San Antonio, Texas.
Christian McNeelyCardiovascular Division, Washington University School of Medicine, St. Louis, Missouri; Barnes-Jewish Hospital, St. Louis, Missouri.
Sunil V RaoThe Duke Clinical Research Institute, Durham, North Carolina.
Duane PintoBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
John A HousePremier, Inc, Premier Applied Sciences, Charlotte, North Carolina.
John C MessengerUniversity of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Richard G BachCardiovascular Division, Washington University School of Medicine, St. Louis, Missouri; Barnes-Jewish Hospital, St. Louis, Missouri.
Abhinav GoyalEmory University, Atlanta, Georgia.
Adhir ShroffUniversity of Illinois at Chicago, Chicago, Illinois.
Samir PancholyGeisinger Commonwealth School of Medicine, Scranton, Pennsylvania.
Steven M BradleyMinneapolis Heart Institute, Minneapolis, Minnesota.
Ty J GluckmanProvidence Heart and Vascular Institute, Portland, Oregon.
Thomas M MaddoxCardiovascular Division, Washington University School of Medicine, St. Louis, Missouri; Barnes-Jewish Hospital, St. Louis, Missouri.
Jason H WasfyMassachusetts General Hospital, Boston, Massachusetts.
Frederick A MasoudiUniversity of Colorado, Anschutz Medical Campus, Aurora, Colorado.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
WASHINGTON UNIVERSITY CER MENTORED CAREER DEVELOPMENT AWARD KM1KM1CA156708 · NCI · WASHINGTON UNIVERSITY · PI FRASER, VICTORIA J. · 2010 to 2010
$2.5M
Washington University Institute of Clinical and Translational SciencesTL1TR000449 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$2.5M
SAFE-PCI: ENHANCING THE SAFETY OF PCI VIA A PATIENT-CENTERED APPROACH TO BLEEDINGR18HS022481 · AHRQ · WASHINGTON UNIVERSITY · PI AMIN, AMIT P. · 2014 to 2014
$429k
AHRQ HHS R18 HS022481NCATS NIH HHS KL2 TR000450NCATS NIH HHS TL1 TR000449NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS KM1 CA156708
6 · The paper itself

Abstract

Acute coronary syndrome (ACS) admissions are common and costly. The association between comprehensive ACS care pathways, outcomes, and costs are lacking. From 434,172 low-risk, uncomplicated ACS patients eligible for early discharge (STEMI 35%, UA/NSTEMI 65%) from the Premier database, we identified ACS care pathways, by stratifying low-risk, uncomplicated STEMI and UA/NSTEMI patients by access site for PCI (trans-radial intervention [TRI] vs transfemoral intervention [TFI]) and by length of stay (LOS). Associations with costs and outcomes (death, bleeding, acute kidney injury, and myocardial infarction at 1-year) were tested using hierarchical, mixed-effects regression, and projections of cost savings with change in care pathways were obtained using modeling. In low-risk uncomplicated STEMI patients, compared with TFI and LOS ≥3 days, a strategy of TRI with LOS <3 days and TFI with LOS <3 days were associated with cost savings of $6,206 and $4,802, respectively. Corresponding cost savings for UA/NSTEMI patients were $7,475 and $6,169, respectively. These care-pathways did not show an excess risk of adverse outcomes. We estimated that >$300 million could be saved if prevalence of the TRI with LOS <3 days and TFI with LOS <3 days strategies are modestly increased to 20% and 70%, respectively. In conclusion, we demonstrate the potential opportunity of cost savings by repositioning ACS care pathways in low-risk and uncomplicated ACS patients, toward transradial access and a shorter LOS without an increased risk of adverse outcomes.

Indexed as

ForecastingPercutaneous Coronary InterventionRegistriesAcute Coronary SyndromeCosts and Cost AnalysisFemaleFollow-Up StudiesHealth Care CostsHumansLength of StayMaleMiddle AgedQuality ImprovementRetrospective StudiesTreatment OutcomeUnited States

Identifiers

PMID31812224
PMCPMC7809633

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.