Evidence map›Paper›PMID 31812155›Full record

ArticlePediatric research2020

Foetal lung volumes in pregnant women who deliver very preterm: a pilot study.

Lisa Story, Tong Zhang, Johannes K Steinweg, Jana Hutter, Jacqueline Matthew, Theodore Dassios, Paul T Seed, Dharmintra Pasupathy, Joanna Allsop, Joseph V Hajnal and 3 more

Abstract read
In one paragraph

Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Functional MRI assessment of the lungs in fetuses that deliver very Preterm: An MRI pilot study.European journal of obstetrics, gynecology, and reproductive biology · 2024
    Article
  8. Observational
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. An automated pipeline for quantitative T2* fetal body MRI and segmentation at low field.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2023
    Article
  15. Assessment of the fetal lungs in utero.American journal of obstetrics & gynecology MFM · 2022
    Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lisa StoryDepartment of Women and Children's Health, King's College London, London, UK. lisa.story@kcl.ac.uk.ORCID http://orcid.org/0000-0001-9328-9592
Tong ZhangDepartment of Perinatal Health and Imaging, King's College London, London, UK.
Johannes K SteinwegDepartment of Perinatal Health and Imaging, King's College London, London, UK.
Jana HutterDepartment of Perinatal Health and Imaging, King's College London, London, UK.
Jacqueline MatthewDepartment of Perinatal Health and Imaging, King's College London, London, UK.
Theodore DassiosDepartment of Women and Children's Health, King's College London, London, UK.
Paul T SeedDepartment of Women and Children's Health, King's College London, London, UK.
Dharmintra PasupathyDepartment of Women and Children's Health, King's College London, London, UK.
Joanna AllsopDepartment of Perinatal Health and Imaging, King's College London, London, UK.
Joseph V HajnalDepartment of Perinatal Health and Imaging, King's College London, London, UK.
Anne GreenoughDepartment of Women and Children's Health, King's College London, London, UK.
Andrew H ShennanDepartment of Women and Children's Health, King's College London, London, UK.
Mary RutherfordDepartment of Perinatal Health and Imaging, King's College London, London, UK.

Funding

Department of HealthMedical Research Council MC_PC_17164Medical Research Council MC_U120088465Wellcome Trust 102431Wellcome Trust 201374Wellcome Trust 201374/Z/16/Z
6 · The paper itself

Abstract

backgroundInfants born preterm are at increased risk of pulmonary morbidity. The contribution of antenatal factors to impairments in lung structure/function has not been fully elucidated. This study aimed to compare standardized lung volumes from foetuses that were delivered <32 weeks' gestation with foetuses that were delivered >37 weeks.

methodsFourteen women who delivered <32 weeks gestation and 56 women who delivered >37 underwent a foetal MRI. Slice-volume reconstruction was then used and the foetal lungs were then segmented using multi-atlas approaches. Body volumes were calculated by manual segmentation and lung:body volume ratios generated.

resultsMean gestation at MRI of the preterm group was 27

conclusionsFoetuses that were delivered very preterm had reduced lung volumes when standardized for foetal size, irrespective of ruptured membranes. These are novel findings and suggest an antenatal aetiology of insult and possible focus for future preventative therapies.

Indexed as

Infant, PrematureMagnetic Resonance ImagingPremature BirthAdultCase-Control StudiesFemaleGestational AgeHumansLungLung Volume MeasurementsMiddle AgedOrgan SizePilot ProjectsPredictive Value of TestsPregnancyProspective Studies

Identifiers

PMID31812155
PMCPMC7610998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.