Evidence map›Paper›PMID 31811981›Full record

ArticleMedical image analysis2020

Atrial scar quantification via multi-scale CNN in the graph-cuts framework.

Lei Li, Fuping Wu, Guang Yang, Lingchao Xu, Tom Wong, Raad Mohiaddin, David Firmin, Jennifer Keegan, Xiahai Zhuang

Abstract read
In one paragraph

Article in Medical image analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lei LiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China; School of Data Science, Fudan University, Shanghai, China.
Fuping WuSchool of Data Science, Fudan University, Shanghai, China; Dept of Statistics, School of Management, Fudan University, Shanghai, China.
Guang YangNational Heart and Lung Institute, Imperial College London, London, UK; Cardiovascular Research Center, Royal Brompton Hospital, London, UK.
Lingchao XuSchool of NAOCE, Shanghai Jiao Tong University, Shanghai, China.
Tom WongCardiovascular Research Center, Royal Brompton Hospital, London, UK.
Raad MohiaddinNational Heart and Lung Institute, Imperial College London, London, UK; Cardiovascular Research Center, Royal Brompton Hospital, London, UK.
David FirminNational Heart and Lung Institute, Imperial College London, London, UK; Cardiovascular Research Center, Royal Brompton Hospital, London, UK.
Jennifer KeeganNational Heart and Lung Institute, Imperial College London, London, UK; Cardiovascular Research Center, Royal Brompton Hospital, London, UK.
Xiahai ZhuangSchool of Data Science, Fudan University, Shanghai, China; Fudan-Xinzailing Joint Research Center for Big Data, Fudan University, Shanghai, China. Electronic address: zxh@fudan.edu.cn.

Funding

British Heart Foundation PG/16/78/32402
6 · The paper itself

Abstract

Late gadolinium enhancement magnetic resonance imaging (LGE MRI) appears to be a promising alternative for scar assessment in patients with atrial fibrillation (AF). Automating the quantification and analysis of atrial scars can be challenging due to the low image quality. In this work, we propose a fully automated method based on the graph-cuts framework, where the potentials of the graph are learned on a surface mesh of the left atrium (LA) using a multi-scale convolutional neural network (MS-CNN). For validation, we have included fifty-eight images with manual delineations. MS-CNN, which can efficiently incorporate both the local and global texture information of the images, has been shown to evidently improve the segmentation accuracy of the proposed graph-cuts based method. The segmentation could be further improved when the contribution between the t-link and n-link weights of the graph is balanced. The proposed method achieves a mean accuracy of 0.856 ± 0.033 and mean Dice score of 0.702 ± 0.071 for LA scar quantification. Compared to the conventional methods, which are based on the manual delineation of LA for initialization, our method is fully automatic and has demonstrated significantly better Dice score and accuracy (p < 0.01). The method is promising and can be potentially useful in diagnosis and prognosis of AF.

Indexed as

Neural Networks, ComputerAtrial FibrillationCatheter AblationCicatrixContrast MediaHeart AtriaHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPulmonary VeinsContrast MediaAtrial fibrillationGraph learningLeft atriumLGE MRIMulti-scale CNNScar segmentation

Identifiers

PMID31811981
PMCPMC6988106

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.