Evidence map›Paper›PMID 31811726›Full record

ArticleThe Journal of physiology2020

Pacemaker function and neural responsiveness of subserosal interstitial cells of Cajal in the mouse colon.

Bernard T Drumm, Benjamin E Rembetski, Katelyn Messersmith, Marena S Manierka, Salah A Baker, Kenton M Sanders

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Impact of acute stress on gastric interstitial cells of Cajal disorder.Frontiers in cell and developmental biology · 2026
    Article
  2. Orai storeoperated CaChannels (Austin, Tex.) · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. CaPhysiological reviews · 2024
    Review
  11. Luteolin ameliorates loperamide-induced functional constipation in mice.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  12. Article
  13. Review
  14. CaThe Journal of physiology · 2022
    Article
  15. CaAdvances in experimental medicine and biology · 2022
    Article
  16. Article
  17. CaeLife · 2021
    Article
  18. Article
  19. Enlightening the frontiers of neurogastroenterology through optogenetics.American journal of physiology. Gastrointestinal and liver physiology · 2020
    Review
  20. Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced CaFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bernard T DrummDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
Benjamin E RembetskiDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
Katelyn MessersmithDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.ORCID 0000-0003-0061-4646
Marena S ManierkaDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
Salah A BakerDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
Kenton M SandersDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.ORCID 0000-0002-4196-1583
University of Nevada, Reno · US

Funding

Tissue, Cell and Tissue Culture CoreP01DK041315 · NIDDK · UNIVERSITY OF NEVADA RENO · PI WARD, SEAN M · 1989 to 2018
$26.3M
Single Cell Molecular ExpressionP30GM110767 · NIGMS · UNIVERSITY OF NEVADA RENO · PI SANDERS, KENTON M · 2014 to 2018
$5.4M
Role of interstitial cells of Cajal in patterned colonic motor activityR01DK120759 · NIDDK · UNIVERSITY OF NEVADA RENO · PI Sal Baker, KENTON M SANDERS · 2019 to 2026
$3.4M
NIDDK NIH HHS P01 DK041315NIDDK NIH HHS R01 DK120759NIGMS NIH HHS P30 GM110767
6 · The paper itself

Abstract

key pointsRhythmic action potentials and intercellular Ca ABSTRACT: Much is known about myogenic mechanisms in circular muscle (CM) in the gastrointestinal tract, although less is known about longitudinal muscle (LM). Two Ca

Indexed as

Biological ClocksCalcium SignalingAnimalsAnoctamin-1ColonInterstitial Cells of CajalMiceMice, Inbred C57BLMuscle ContractionMuscle, SmoothANO1 protein, mouseAnoctamin-1Ca2+ imagingCa2+ storesc-Kitcolongastrointestinal motilityoptogeneticsSIP syncytium

Identifiers

PMID31811726
PMCPMC7024031
OpenAlexW2992458745

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.