Evidence map›Paper›PMID 31811592›Full record

ArticleJournal of community genetics2020

African American mothers' attitudes towards genetic testing in the InterGEN study.

Michelle L Wright, Kevin Newhall, Veronica Barcelona, Jacquelyn Y Taylor

Abstract read
In one paragraph

Article in Journal of community genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michelle L WrightSchool of Nursing, University of Texas, Austin, TX, USA. michelle.wright@utexas.edu.ORCID http://orcid.org/0000-0002-9348-8740
Kevin NewhallDepartment of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY, USA.
Veronica BarcelonaYale School of Nursing, Orange, CT, USA.
Jacquelyn Y TaylorNew York University, Rory Meyers College of Nursing, New York, NY, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI Catherine A Calder · 2017 to 2026
$5.2M
Intergenerational Impact of Genetic and Psychological Factors on Blood PressureR01NR013520 · NINR · YALE UNIVERSITY · PI TAYLOR, JACQUELYN Y · 2014 to 2019
$3.9M
DNA Methylation, Preterm Birth and Blood Pressure in African American ChildrenK01NR017010 · NINR · YALE UNIVERSITY · PI BARCELONA, VERONICA · 2017 to 2019
$278k
The Microbiome of Pregnant African American Women with Group B Streptococcus Colonization and the Influence of Prenatal AntibioticsK01NR017903 · NINR · UNIVERSITY OF TEXAS AT AUSTIN · PI WRIGHT, MICHELLE LYNN · 2018 to 2020
$271k
NCATS NIH HHS UL1 TR001863NICHD NIH HHS P2C HD042849NINR NIH HHS K01NR017010NINR NIH HHS K01 NR017903NINR NIH HHS K01NR017903NINR NIH HHS R01 NR013520NINR NIH HHS R01NR013520
6 · The paper itself

Abstract

The paucity of representation of people of color, particularly those of African ancestry, is a major issue in contemporary omics research. Metadata summarizing genome-wide association studies from 2005 to 2015 suggest that nearly 80% of participants are of European ancestry and only 2.4% are of African ancestry. Negative attitude towards genetic testing is a commonly cited belief as to why there is low representation of Americans of African ancestry participating in genetic studies. Using the attitudes towards genetic testing survey, administered as part of our parent (epi)genome-wide association study, we characterized the perceptions of genetic research among our cohort of African ancestry women (n = 168). Our data show generally favorable perceptions of genetic testing among our cohort. Further, we demonstrate that more favorable attitudes towards genetic testing correlated with higher levels of income, even when accounting for commonly cited negative predictors such as maternal age, education, country of origin, and religion. Overall, our data characterize generally positive perceptions of genetic testing among women of African ancestry.

Indexed as

(4-6) Genetic testingAfrican AmericanAttitudesInterGENWomen

Identifiers

PMID31811592
PMCPMC7295918

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.