Evidence map›Paper›PMID 31811531›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

Adapted physical activity and therapeutic exercise in late-onset Pompe disease (LOPD): a two-step rehabilitative approach.

Giovanni Iolascon, Michele Vitacca, Elena Carraro, Carmelo Chisari, Pietro Fiore, Sonia Messina, Tiziana Mongini, Antimo Moretti, Valeria A Sansone, Antonio Toscano and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Management of Pompe disease alongside and beyond ERT: a narrative review.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2025
    Review
  3. Article
  4. Management of motor rehabilitation in individuals with muscular dystrophies. 1Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Giovanni IolasconDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Via De Crecchio 4, 80138, Naples, Italy. giovanni.iolascon@gmail.com.ORCID https://orcid.org/0000-0002-0976-925X
Michele VitaccaFERS Respiratory Rehabilitation Unit, ICS S. Maugeri IRCCS, Lumezzane, BS, Italy.
Elena CarraroNeuroMuscular Omnicentre, Fondazione Serena Onlus, Neurorehabilitation Unit, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0002-1259-1050
Carmelo ChisariUnit of Neurorehabilitation, Department of Medical Specialties, University Hospital of Pisa, Pisa, Italy.ORCID https://orcid.org/0000-0002-1043-7738
Pietro FioreDepartment of Basic Sciences, Neuroscience and Sense Organs, University of Bari "Aldo Moro", Bari, Italy.
Sonia MessinaNeurology and Neuromuscular Unit, University of Messina, Messina, Italy.ORCID https://orcid.org/0000-0001-7994-3391
Tiziana MonginiNeuromuscular Unit, Department of Neurosciences, University of Turin, Turin, Italy.
Antimo MorettiDepartment of Medical and Surgical Specialties and Dentistry, University of Campania "Luigi Vanvitelli", Via De Crecchio 4, 80138, Naples, Italy.ORCID https://orcid.org/0000-0002-4598-2891
Valeria A SansoneNeuroMuscular Omnicentre, Fondazione Serena Onlus, Neurorehabilitation Unit, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0002-1354-3800
Antonio ToscanoNeurology and Neuromuscular Unit, University of Messina, Messina, Italy.ORCID https://orcid.org/0000-0002-3995-4827
Gabriele SicilianoDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID https://orcid.org/0000-0002-6142-2384
AIM (Italian Association of Myology), AIPO (Italian Association of Hospital Pulmonologists), SIRN (Italian Society of Neurorehabilitation), and SIMFER (Italian Society of Physical Medicine and Rehabilitation)
Centro Clinico Nemo · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Messina · ITAzienda Ospedaliera Universitaria Pisana · ITIstituti Clinici Scientifici Maugeri · ITUniversity of Bari Aldo Moro · ITUniversity of Pisa · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aerobic exercise, training to sustain motor ability, and respiratory rehabilitation may improve general functioning and quality of life (QoL) in neuromuscular disorders. Patients with late-onset Pompe disease (LOPD) typically show progressive muscle weakness, respiratory dysfunction and minor cardiac involvement. Characteristics and modalities of motor and respiratory rehabilitation in LOPD are not well defined and specific guidelines are lacking. Therefore, we evaluated the role of physical activity, therapeutic exercise, and pulmonary rehabilitation programs in order to promote an appropriate management of motor and respiratory dysfunctions and improve QoL in patients with LOPD. We propose two operational protocols: one for an adapted physical activity (APA) plan and the other for an individual rehabilitation plan, particularly focused on therapeutic exercise (TE) and respiratory rehabilitation.

Indexed as

ExerciseAdolescentAdultAge of OnsetBicyclingBreathing ExercisesChildClinical ProtocolsExercise TherapyGlycogen Storage Disease Type IIHumansMuscle Stretching ExercisesMuscular DiseasesResistance TrainingAdapted physical activityGlycogen storage disease type IIICFPompe diseaseRehabilitationTherapeutic exercise

Identifiers

PMID31811531
OpenAlexW2991995856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.