Evidence map›Paper›PMID 31811458›Full record

ArticleNeurochemical research2020

Pramipexole Inhibits MPP

Chao Deng, Jianping Zhu, Junlan Yuan, Yong Xiang, Li Dai

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. HOTAIRM1 knockdown reduces MPPTranslational neuroscience · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Berberine Attenuates MPPNeurochemical research · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chao DengDepartment of Neurology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang Road, Shiyan City, 442000, Hubei Province, China.
Jianping ZhuDepartment of Neurology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang Road, Shiyan City, 442000, Hubei Province, China.
Junlan YuanDepartment of Neurology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang Road, Shiyan City, 442000, Hubei Province, China.
Yong XiangDepartment of Neurology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang Road, Shiyan City, 442000, Hubei Province, China.
Li DaiDepartment of Neurology, Renmin Hospital, Hubei University of Medicine, 39 Chaoyang Road, Shiyan City, 442000, Hubei Province, China. liqinyaojaehj@163.com.ORCID http://orcid.org/0000-0002-6306-1316
Hubei University of Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pramipexole (PPX) is a common drug for the treatment of Parkinson's disease. However, the mechanism allows PPX in the progression of Parkinson's disease remains largely unknown. This study aimed to investigate the role of PPX in 1-Methyl-4-phenylpyridinium (MPP

Indexed as

1-Methyl-4-phenylpyridiniumAntiparkinson AgentsApoptosisBrain-Derived Neurotrophic FactorCell Line, TumorDown-RegulationGene Knockdown TechniquesHumansMicroRNAsOxidative StressPramipexoleUp-Regulation1-Methyl-4-phenylpyridiniumAntiparkinson AgentsBDNF protein, humanBrain-Derived Neurotrophic FactorMicroRNAsMIRN494 microRNA, humanPramipexoleBDNFmiR-494-3pNeurotoxicityParkinson’s diseasePramipexole

Identifiers

PMID31811458
OpenAlexW2994167464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.