Evidence map›Paper›PMID 31811244›Full record

ArticleScientific reports2019

A Deep Learning Framework for Design and Analysis of Surgical Bioprosthetic Heart Valves.

Aditya Balu, Sahiti Nallagonda, Fei Xu, Adarsh Krishnamurthy, Ming-Chen Hsu, Soumik Sarkar

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 60 citations in OpenAlex.

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  11. Parameterization, geometric modeling, and isogeometric analysis of tricuspid valves.Computer methods in applied mechanics and engineering · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aditya BaluIowa State University, Department of Mechanical Engineering, Ames, Iowa, 50011, USA.
Sahiti NallagondaIowa State University, Department of Mechanical Engineering, Ames, Iowa, 50011, USA.
Fei XuIowa State University, Department of Mechanical Engineering, Ames, Iowa, 50011, USA.ORCID http://orcid.org/0000-0001-5361-4231
Adarsh KrishnamurthyIowa State University, Department of Mechanical Engineering, Ames, Iowa, 50011, USA. adarsh@iastate.edu.ORCID http://orcid.org/0000-0002-5900-1863
Ming-Chen HsuIowa State University, Department of Mechanical Engineering, Ames, Iowa, 50011, USA.
Soumik SarkarIowa State University, Department of Mechanical Engineering, Ames, Iowa, 50011, USA.
Iowa State University · US

Funding

Biomechanical indicators of bicuspid aortic valve dysfunctionR01HL142504 · NHLBI · UNIVERSITY OF TEXAS AT AUSTIN · PI GORMAN, ROBERT C, HSU, MING-CHEN · 2018 to 2021
$2.9M
Novel Simulation Technologies for BHV Long-Term DurabilityR01HL129077 · NHLBI · UNIVERSITY OF TEXAS AT AUSTIN · PI HUGHES, THOMAS J., MANNING, KEEFE B · 2016 to 2019
$2.1M
NSF | ENG/OAD | Division of Civil, Mechanical and Manufacturing Innovation (CMMI) CMMI:1644441U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL129077U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL142504
6 · The paper itself

Abstract

Bioprosthetic heart valves (BHVs) are commonly used as heart valve replacements but they are prone to fatigue failure; estimating their remaining life directly from medical images is difficult. Analyzing the valve performance can provide better guidance for personalized valve design. However, such analyses are often computationally intensive. In this work, we introduce the concept of deep learning (DL) based finite element analysis (DLFEA) to learn the deformation biomechanics of bioprosthetic aortic valves directly from simulations. The proposed DL framework can eliminate the time-consuming biomechanics simulations, while predicting valve deformations with the same fidelity. We present statistical results that demonstrate the high performance of the DLFEA framework and the applicability of the framework to predict bioprosthetic aortic valve deformations. With further development, such a tool can provide fast decision support for designing surgical bioprosthetic aortic valves. Ultimately, this framework could be extended to other BHVs and improve patient care.

Indexed as

Computer-Aided DesignDeep LearningBiomechanical PhenomenaBioprosthesisDecision Support TechniquesFeasibility StudiesFinite Element AnalysisHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHeart ValvesHumansImage Processing, Computer-AssistedModels, CardiovascularProsthesis DesignProsthesis FailureTomography, X-Ray Computed

Identifiers

PMID31811244
PMCPMC6898064
OpenAlexW2991899124

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.