Evidence map›Paper›PMID 31811207›Full record

ArticleScientific reports2019

Chronic Disease Onset Among People Living with HIV and AIDS in a Large Private Insurance Claims Dataset.

Hsin-Yun Yang, Matthew R Beymer, Sze-Chuan Suen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hsin-Yun YangDepartment of Pharmaceutical and Health Economics, School of Pharmacy, University of Southern California, Los Angeles, USA.
Matthew R BeymerDepartment of Community Health Sciences, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, Los Angeles, USA.
Sze-Chuan SuenDaniel J. Epstein Department of Industrial and Systems Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, USA. ssuen@usc.edu.ORCID http://orcid.org/0000-0001-9453-5863

Funding

USC-Yale Roybal Center for Behavioral Interventions in AgingP30AG024968 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JASON N. DOCTOR · 2004 to 2026
$14.7M
USC Resource Center for Minority Aging Research (US-RCMAR)P30AG043073 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI EMMA AGUILA, JENNIFER A AILSHIRE · 2012 to 2026
$10.1M
NIA NIH HHS P30 AG024968NIA NIH HHS P30 AG043073
6 · The paper itself

Abstract

People living with HIV/AIDS (PLWHA) have a growing life expectancy in the US due to early provision of effective antiretroviral treatment. This has resulted in increasing exposure to age-related chronic illness that may be exacerbated by HIV/AIDS or antiretroviral treatment. Prior work has suggested that PLWHA may be subject to accelerated aging, with earlier onset and higher risk of acquiring many chronic illnesses. However, the magnitude of these effects, controlling for chronic co-morbidities, has not been fully quantified. We evaluate the magnitude of association of HIV infection on developing chronic conditions while controlling for demographics, behavioral risk factors, and chronic comorbidities. We compare chronic disease risks of diabetes, hypertension, stroke, cancers, lung diseases, cardiovascular diseases, and cognitive impairment between PLWHA and HIV- individuals in a large, de-identified private insurance claims dataset (~24,000 PLWHA) using logistic regressions. HIV status is statistically significantly associated with higher levels for all chronic illnesses examined, a result which is robust to multiple model specifications and duration of analysis (2, 5, and 10 years from enrollment). Our results suggest that PLWHA may be at elevated risk for a wide variety of chronic illnesses and may require additional care as the aging PLWHA population grows.

Indexed as

Chronic DiseaseComorbidityAcquired Immunodeficiency SyndromeAgedAnti-HIV AgentsCardiovascular DiseasesDatabases, FactualDementiaDiabetes ComplicationsFemaleHIV InfectionsHumansHypertensionInsurance, HealthLung DiseasesMaleAnti-HIV Agents

Identifiers

PMID31811207
PMCPMC6897968

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.