Evidence map›Paper›PMID 31810987›Full record

ArticleGenetics2020

WormCat: An Online Tool for Annotation and Visualization of

Amy D Holdorf, Daniel P Higgins, Anne C Hart, Peter R Boag, Gregory J Pazour, Albertha J M Walhout, Amy K Walker

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 279 citations in OpenAlex.

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  9. Vitamin BNature communications · 2026
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104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Amy D HoldorfProgram in Systems Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605.
Daniel P HigginsDepartment of Computer Science, Georgia Technical University, Atlanta, Georgia 30332-0765.ORCID 0000-0002-4660-354X
Anne C HartDepartment of Neuroscience, Robert J. and Nancy D. Carney Institute for Brain Science, Brown University, Providence, Rhode Island 02912.ORCID 0000-0001-7239-4350
Peter R BoagDepartment of Biochemistry and Molecular Biology, Monash University, 3800 Clayton Australia.ORCID 0000-0002-0889-0859
Gregory J PazourProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605.ORCID 0000-0002-6285-8796
Albertha J M WalhoutProgram in Systems Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605.ORCID 0000-0001-5587-3608
Amy K WalkerProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605 amy.walker@umassmed.edu.ORCID 0000-0003-1899-8916
University of Massachusetts Chan Medical School · USAllen Institute for Brain Science · USGeorgia Institute of Technology · USMonash University · AU

Funding

Transcription networks in C elegans organogenesisR01DK068429 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI A. J. Marian Walhout · 2005 to 2026
$10.9M
Intraflagellar Transport Proteins in MiceR01GM060992 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Gregory J Pazour · 2001 to 2026
$10.3M
Gene regulatory and metabolic network structure, function and evolutionR35GM122502 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI A. J. Marian Walhout · 2017 to 2026
$8.3M
Role of methylation-dependent pathways in aging and stressR01AG053355 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Amy Karol Walker · 2017 to 2026
$4.5M
Gene Regulatory Networks in Development and PhysiologyR56DK068429 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WALHOUT, A. J. MARIAN · 2018 to 2018
$671k
NIA NIH HHS R01 AG053355NIDDK NIH HHS R01 DK068429NIDDK NIH HHS R56 DK068429NIGMS NIH HHS R01 GM060992NIGMS NIH HHS R35 GM122502
6 · The paper itself

Abstract

The emergence of large gene expression datasets has revealed the need for improved tools to identify enriched gene categories and visualize enrichment patterns. While gene ontogeny (GO) provides a valuable tool for gene set enrichment analysis, it has several limitations. First, it is difficult to graph multiple GO analyses for comparison. Second, genes from some model systems are not well represented. For example, ∼30% of

Indexed as

AlgorithmsAnimalsCaenorhabditis elegansDatabases, GeneticGene Expression ProfilingGenomeMolecular Sequence AnnotationTranscriptomeC. elegansgene set enrichment analysisRNA sequencing visualization

Identifiers

PMID31810987
PMCPMC7017019
OpenAlexW2993507558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.