Evidence map›Paper›PMID 31810883›Full record

ArticleImmunity2019

CD4

Ryan Zander, David Schauder, Gang Xin, Christine Nguyen, Xiaopeng Wu, Allan Zajac, Weiguo Cui

Open access · greenAbstract readComment
In one paragraph

Article in Immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 430 papers.

0numbers the graph read from it
0cells of the map it votes in
430citing papers in PubMed
27.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

430 citing papers in PubMed, 631 citations in OpenAlex.

  1. Trial
  2. Virulence · 2026
    Article
  3. Article
  4. ANKRD11 deficiency reprograms CD8Nature immunology · 2026
    Article
  5. Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026
    Review
  6. Article
  7. Article
  8. Antigen-experienced airway CD8Science advances · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. CD4Science (New York, N.Y.) · 2026
    Article

370 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ryan ZanderBlood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53213, USA.
David SchauderDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Gang XinBlood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53213, USA.
Christine NguyenDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Xiaopeng WuBlood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53213, USA.
Allan ZajacDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Weiguo CuiBlood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI 53213, USA; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: weiguo.cui@bcw.edu.
Medical College of Wisconsin · USVersiti Blood Center of Wisconsin · USUniversity of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Medical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7M
Regulation of T Cell Activity During Chronic InfectionsR01AI049360 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZAJAC, ALLAN J · 2001 to 2019
$4.1M
The Cellular and Transcriptional Control of CD8 T Cell Functional Adaptation to Chronic VirusesR01AI125741 · NIAID · VERSITI WISCONSIN, INC. · PI CUI, WEIGUO · 2016 to 2020
$2.1M
BATF-IRF4 complex controls transcriptional regulation and effector function of autoreactive CD8 T cells in type 1 diabetesF30DK108557 · NIDDK · VERSITI WISCONSIN, INC. · PI SCHAUDER, DAVID · 2016 to 2019
$191k
NCI NIH HHS P30 CA013148NIAID NIH HHS R01 AI049360NIAID NIH HHS R01 AI125741NIDDK NIH HHS F30 DK108557NIGMS NIH HHS T32 GM080202
6 · The paper itself

Abstract

Although CD4

Indexed as

InfectionsNeoplasmsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansProgrammed Cell Death 1 ReceptorT-Lymphocyte SubsetsProgrammed Cell Death 1 ReceptorCD4(+) T cell helpCD8(+) T cell heterogeneityLCMV Cl13

Identifiers

PMID31810883
PMCPMC6929322
OpenAlexW2994331021

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.