ArticleImmunity2020
Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes.
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Article in Immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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56citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
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Who cites it
56 citing papers in PubMed, 114 citations in OpenAlex.
- Correlational Analysis of Liver Metabolites and Pharmacodynamic Indexes in Xanthoxylin-Treated Acute Liver Failure.Molecules (Basel, Switzerland) · 2026Article
- Transcriptional Profile Change of NK-92 Cells in Presence of Cytokines, TGFβ Signaling Pathway Inhibitor and CDK7/12/13 Kinase Inhibitor.International journal of molecular sciences · 2026Article
- Human type-1 innate lymphoid cells control leukemia stem cell differentiation and limit acute myeloid leukemia development.Nature communications · 2026Article
- Granzyme A-producing type 1 innate lymphoid cells promote salivary secretion in the aged submandibular gland.Inflammation and regeneration · 2026Article
- SSRIs-induced liver injury adverse events: a data-based retrospective study and investigation of potential toxicological mechanisms.Frontiers in pharmacology · 2026Article
- Characterization of innate lymphoid cells in infants with human cytomegalovirus infection.BMC pediatrics · 2025Article
- Discovery of intrahepatic CD103Experimental & molecular medicine · 2025Article
- Type 1 innate lymphoid cell-immature neutrophil axis suppresses acute tissue inflammation.Nature communications · 2025Article
- Group 1 innate lymphoid cells protect liver transplants from ischemia-reperfusion injury via an interferon gamma-mediated pathway.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025Article
- Role of liver-resident NK cells in liver immunity.Hepatology international · 2025Review
- Antigen-presenting innate lymphoid cells induced by BCG vaccination promote a respiratory antiviral immune response through the skin‒lung axis.Cellular & molecular immunology · 2025Article
- A membrane lipid signature unravels the dynamic landscape of group 1 innate lymphoid cells across the health-disease continuum.iScience · 2025Article
- Fecal microbiota transplantation improves hepatic steatosis induced by HFD in a mouse model associated with liver ILC1 regulation and indole-3-carbinol level.Frontiers in nutrition · 2025Article
- Ccl2-Induced Regulatory T Cells Balance Inflammation Through Macrophage Polarization During Liver Reconstitution.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Sepsis induced dysfunction of liver type 1 innate lymphoid cells.BMC immunology · 2024Article
- Article
- Interleukin-7-based identification of liver lymphatic endothelial cells reveals their unique structural features.JHEP reports : innovation in hepatology · 2024Article
- Microcirculatory disturbance in acute liver injury is triggered by IFNγ-CD40 axis.Journal of inflammation (London, England) · 2024Article
- Group 1 ILCs: Heterogeneity, plasticity, and transcriptional regulation.Immunological reviews · 2024Review
- The role of trained immunity in sepsis.Frontiers in immunology · 2024Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Tsukasa NabekuraLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan; Department of Immunology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan; R&D Center for Innovative Drug Discovery, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Luke RigganMolecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Andrew D HildrethMolecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Timothy E O'SullivanMolecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095, USA.
Akira ShibuyaLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan; Department of Immunology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan; R&D Center for Innovative Drug Discovery, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. Electronic address: ashibuya@md.tsukuba.ac.jp.
University of California, Los Angeles · USUniversity of Tsukuba · JP
Funding
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PETER J TONTONOZ · 2003 to 2026
$40.4MMULTIDISCIPLINARY TRAINING IN MICROBIAL PATHOGENESIST32AI007323 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Peter John Bradley · 1988 to 2026
$8.6MTranscriptional mechanisms of natural killer cell responses during mouse cytomegalovirus infectionR01AI145997 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI O'SULLIVAN, TIMOTHY E · 2019 to 2023
$2.3MNIAID NIH HHS R01 AI145997NIAID NIH HHS T32 AI007323NIDDK NIH HHS P30 DK063491
Abstract
Although type 1 innate lymphoid cells (ILC1s) have been originally found as liver-resident ILCs, their pathophysiological role in the liver remains poorly investigated. Here, we demonstrated that carbon tetrachloride (CCl
Indexed as
Adenosine TriphosphateAnimalsAntigens, Differentiation, T-Lymphocytebcl-X ProteinCarbon TetrachlorideCells, CulturedChemical and Drug Induced Liver InjuryFemaleHepatocytesInterferon-gammaInterleukin-12 Subunit p35Killer Cells, NaturalLiverLymphocyte ActivationLymphocytesMiceAdenosine TriphosphateAntigens, Differentiation, T-LymphocyteBcl2l1 protein, mousebcl-X ProteinCarbon TetrachlorideIFNG protein, mouseIl12a protein, mouseInterferon-gammaInterleukin-12 Subunit p35T Lineage-Specific Activation Antigen 1acute liver injuryATPBcl-xLCCl(4)DNAM-1hepatocyteIFN-γIL-12IL-7ILC1
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.