Evidence map›Paper›PMID 31810411›Full record

ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2021

Validation of an app-based portable spirometer in adolescents with asthma.

Brian Ring, Allison J Burbank, Katherine Mills, Sally Ivins, James Dieffenderfer, Michelle L Hernandez

Abstract read
In one paragraph

Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Spirometry Monitoring and Asthma Responsibility in Kids (SMARt-Kids): A Mixed-Methods Study.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners · 2026
    Article
  3. Review
  4. Review
  5. Mobile Health for Asthma.CHEST pulmonary · 2023
    Review
  6. Clinical Trial Design Innovations for Precision Medicine in Asthma.Advances in experimental medicine and biology · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian RingCenter for Environmental Medicine, Asthma, & Lung Biology, The University of North Carolina, Chapel Hill, Raleigh, NC, USA.
Allison J BurbankCenter for Environmental Medicine, Asthma, & Lung Biology, The University of North Carolina, Chapel Hill, Raleigh, NC, USA.
Katherine MillsCenter for Environmental Medicine, Asthma, & Lung Biology, The University of North Carolina, Chapel Hill, Raleigh, NC, USA.
Sally IvinsCenter for Environmental Medicine, Asthma, & Lung Biology, The University of North Carolina, Chapel Hill, Raleigh, NC, USA.
James DieffenderferNSF Nanosystems Engineering Research Center for Advanced Self-Powered Systems of Integrated Sensors and Technologies (ASSIST), North Carolina State University, Raleigh, NC, USA.
Michelle L HernandezCenter for Environmental Medicine, Asthma, & Lung Biology, The University of North Carolina, Chapel Hill, Raleigh, NC, USA.

Funding

IL-1 receptor blockade as a novel treatment for exacerbation of allergic airway responses in humansR01HL135235 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HERNANDEZ, MICHELLE · 2017 to 2021
$2.7M
NHLBI NIH HHS R01 HL135235
6 · The paper itself

Abstract

objectivesObjective measurements of asthma impairment could aid teens in recognition of changes in asthma status over time. Ready access to a conventional spirometer is not realistic outside of the clinical setting. In this proof-of-concept study, we compared the performance of the VitalFlo mobile spirometer to the nSpire KoKo® sx1000 spirometer for accuracy in measuring Forced Expiratory Volume in one second (FEV

methodsTwo hundred forty pulmonary function measurements were collected from 48 adolescents with persistent asthma from the University of North Carolina's pediatric allergy and pulmonology subspecialty clinics. Participants performed spirometry with the nSpireKoKo® sx1000 spirometer and the VitalFlo spirometer during their clinic visits. 119 simulated FVC maneuvers were conducted on both devices to standardize measurements. Pearson correlations, Bland-Altman procedure, and two-sample comparison tests were performed to assess the relationship between the two spirometers.

resultsVitalFlo measurements were significantly highly correlated with nSpireKoKo® spirometer values for FEV

conclusionsLung function measurements from the VitalFlo mobile spirometer were comparable to a commercially-available spirometer commonly used in clinical settings. This validated app-based spirometer for home use has the potential to improve asthma self-management.

Indexed as

Mobile ApplicationsAdolescentAsthmaChildFemaleHumansMaleMonitoring, AmbulatorySelf-ManagementSensitivity and SpecificitySpirometryadolescentAsthmabronchial diseasescontrolimmediate hypersensitivityNCT02662413NCT02671643obstructive lung diseasesrespiratory hypersensitivityrespiratory tract disease

Identifiers

PMID31810411
PMCPMC7282988

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.