Evidence map›Paper›PMID 31810408›Full record

ArticleHuman vaccines & immunotherapeutics2020

Co-administration of vaccines: a focus on tetravalent Measles-Mumps-Rubella-Varicella (MMRV) and meningococcal C conjugate vaccines.

Paolo Bonanni, Sara Boccalini, Angela Bechini, Ornella Varone, Giulio Matteo, Federica Sandri, Giovanni Gabutti

Open access · hybridAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  13. Meningococcal Disease in Pediatric Age: A Focus on Epidemiology and Prevention.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Paolo BonanniDepartment of Health Sciences, University of Florence , Florence, Italy.ORCID 0000-0003-2875-3744
Sara BoccaliniDepartment of Health Sciences, University of Florence , Florence, Italy.ORCID 0000-0002-9695-7549
Angela BechiniDepartment of Health Sciences, University of Florence , Florence, Italy.ORCID 0000-0002-6013-8779
Ornella VaroneSpecialization Medical School of Hygiene and Preventive Medicine, University of Florence , Florence, Italy.
Giulio MatteoSpecialization Medical School of Hygiene and Preventive Medicine, University of Ferrara , Ferrara, Italy.ORCID 0000-0001-9654-0420
Federica SandriSpecialization Medical School of Hygiene and Preventive Medicine, University of Ferrara , Ferrara, Italy.ORCID 0000-0001-7865-4598
Giovanni GabuttiDepartment of Medical Sciences, University of Ferrara , Ferrara, Italy.
University of Florence · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simultaneous administration of different vaccines is a strategy to increase the possibility to receive vaccines at appropriate age, safely and effectively, reducing the number of sessions and allowing a more acceptable integration of new vaccines into National Immunization Programs (NIPs). Co-administration can be performed when there are specific indications in the Summary of Product Characteristics (SmPC) of the vaccines; but, in absence of these indications, the practice is possible if there are no specific contraindications nor scientific evidence to discourage simultaneous administration. The aim of this work is to review the safety and efficacy of co-administration of the tetravalent measles, mumps, rubella, and varicella (MMRV) and the meningococcal C (Men C) conjugate vaccines after 12 months of age. Several studies demonstrated that MMRV and Men C conjugate vaccines can be administered concomitantly without a negative impact on the safety and immunogenicity of either vaccines, inducing highly immunogenic responses.

Indexed as

ChickenpoxMeaslesMumpsRubellaAntibodies, ViralChickenpox VaccineFeverHumansInfantMaleMeasles-Mumps-Rubella VaccineVaccines, CombinedVaccines, ConjugateAntibodies, ViralChickenpox VaccineMeasles-Mumps-Rubella VaccineVaccines, CombinedVaccines, ConjugateCo-administrationEfficacyMeaslesMeningococcal C vaccineMumpsRubellaSafetyVaricella vaccine

Identifiers

PMID31810408
PMCPMC7482742
OpenAlexW2993560537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.