ArticleAnimals : an open access journal from MDPI2019
Composition and Factors Affecting Quality of Bovine Colostrum: A Review.
Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 187 citations in OpenAlex.
- Bovine Colostrum in Increased Intestinal Permeability in Healthy Athletes and Patients: A Meta-Analysis of Randomized Clinical Trials.Digestive diseases and sciences · 2024Pooled it
- Pooled it
- Post-Delivery Milking Delay Influence on the Effect of Oral Supplementation with Bovine Colostrum as Measured with Intestinal Permeability Test.Medicina (Kaunas, Lithuania) · 2020Trial
- Biotechnological Advancements in Ovine Bioactives: Mapping Protein Expression Trends and Immuno-Lipidomic Dynamics for Functional Food Applications.International journal of molecular sciences · 2026Article
- Impact of Dam Lactation Number on Colostrum Quality, Calf Growth, and Economic Performance in Holstein Cows.Veterinary sciences · 2026Article
- Effect of Colostrum Components on Early Inflammatory Response, IgG Concentration and Weight Gain in Lambs.Animals : an open access journal from MDPI · 2026Article
- Impact of chronic cold stress on metabolism, colostrum quality, and lamb performance in locally adapted ewes.Tropical animal health and production · 2026Article
- Perinatal physiology and welfare in water buffalo: calving, mother-calf bonding, lactation, and postpartum disorders.Frontiers in veterinary science · 2026Review
- Physicochemical composition and long-chain fatty acids in fresh and freeze-dried colostrum from cows and buffaloes.Frontiers in veterinary science · 2026Article
- Article
- The Microbial Composition of Bovine Colostrum as Influenced by Antibiotic Treatment.Antibiotics (Basel, Switzerland) · 2025Article
- Biotechnology Approaches to Dairy Alternatives Through Precision Fermentation and Cellular Agriculture.Food science of animal resources · 2025Review
- Pre-partum feeding strategies affect colostrum metabolite levels related to nitrogen and energy metabolism in Holstein dairy cows.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- The effects of colostrum nutritional components, colostrum and serum bioactive substances on the morbidity, mortality and growth performance of water buffalo (Bubalus bubalis) calves until weaning.Tropical animal health and production · 2025Article
- Influence of Capsaicin Supplementation on the Enhancement of Passive Immunity Transfer Through Modulation of Immunoglobulin Absorption in Neonatal Calves.Animals : an open access journal from MDPI · 2025Article
- Pathological Investigation of the Effect of Bovine Colostrum Against 5-FU-Induced Liver, Kidney, and Heart Toxicity in Rats.Life (Basel, Switzerland) · 2025Article
- Effects of Botanical Blend of Turmeric, Capsicum, and Pepper Extracts on Colostrum and Milk Yield and Quality, Passive Transfer of Immunity, and Performance of Beef Cow-Calf Pairs.Veterinary sciences · 2025Article
- Potential of Encapsulated Bovine Colostrum in Powder-Based Formulations for Facial Clay, Peel-Off Gel, and Sleeping Gel Masks.Gels (Basel, Switzerland) · 2025Article
- Effect of Bovine Colostrum on Canine Immune Health.Animals : an open access journal from MDPI · 2025Review
- Bovine Colostrum in Pediatric Nutrition and Health.Nutrients · 2024Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colostrum as a secretion of the mammary gland is produced and accumulated in the final stage of pregnancy and in the first days after calving. It is designed to provide the calf with the necessary nutrients and biologically active ingredients. One of the most difficult periods in the life of animals is their rearing, and the most sensitive are the first days after birth. This is the time when most falls occur, and they are caused by mortality and morbidity, even at the level of 30%. Such losses affect the performance and profitability of animal production (the percentage of animals intended for reproduction or fattening is reduced and the intensity of selection in the herd is also reduced). Both diseases and mortality are the cause of serious economic, production, and breeding losses, which are the result of weak immune mechanisms. The adaptability of calves to the environment is determined by their immune status. Colostrum has a regulating function and stimulates the young organism to grow, and it has properties that support the functioning of systems: Endocrine and immunological. For colostrum to fulfil its role, it must be administered immediately after birth, because the immunoglobulins it contains are absorbed during the first 16-27 h after the birth of the calf, preferably within 2-4 h of age. Blood from calves that have been properly calved should have an antibody concentration of 15g/L (24-48 h of age). Therefore, immunoglobulins are the most important factor affecting infectious immunity; an adequate concentration of immunoglobulins in calves' blood is related to their survival and health. It is the intent of this review to synthesize and summarize the information currently available on colostrum, as well as to discuss the interpretation of the results.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.