Evidence map›Paper›PMID 31810286›Full record

ArticleBiomolecules2019

Functional Group-Dependent Induction of Astrocytogenesis and Neurogenesis by Flavone Derivatives.

Ha-Rim Lee, Jin Mi Kang, Young Min Kim, Sagang Kim, Jihyae Ann, Jeewoo Lee, Hyun-Jung Kim

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Study on Active Components ofMolecules (Basel, Switzerland) · 2021
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ha-Rim LeeCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Jin Mi KangCollege of Pharmacy, Seoul National University, Seoul 08826, Korea.
Young Min KimCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Sagang KimCollege of Pharmacy, Seoul National University, Seoul 08826, Korea.
Jihyae AnnCollege of Pharmacy, Seoul National University, Seoul 08826, Korea.
Jeewoo LeeCollege of Pharmacy, Seoul National University, Seoul 08826, Korea.
Hyun-Jung KimCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea.
Seoul National University · KRChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural stem cells (NSCs) differentiate into multiple cell types, including neurons, astrocytes, and oligodendrocytes, and provide an excellent platform to screen drugs against neurodegenerative diseases. Flavonoids exert a wide range of biological functions on several cell types and affect the fate of NSCs. In the present study, we investigated whether the structure-activity relationships of flavone derivatives influence NSC differentiation. As previously reported, we observed that PD98059 (2'-amino-3'-methoxy-flavone), compound

Indexed as

AnimalsAstrocytesCells, CulturedFlavonesGlial Fibrillary Acidic ProteinNeural Stem CellsNeurogenesisNeuronsRats, Sprague-DawleyTubulinFlavonesGfap protein, ratGlial Fibrillary Acidic ProteinTubulinastrocytogenesisdifferentiationflavoneneural stem cellsneurogenesisstructure-activity relationships

Identifiers

PMID31810286
PMCPMC6995541
OpenAlexW2991534707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.